Page 80 - Read Online

Page 14 of 15 Miliotis et al. J Cancer Metastasis Treat 2020;6:13 I http://dx.doi.org/10.20517/2394-4722.2020.12

73. Yoon CJ, Chang MS, Kim DH, Kim W, Koo BK, et al. Epstein-Barr virus-encoded miR-BART5-5p upregulates PD-L1 through PIAS3/
pSTAT3 modulation, worsening clinical outcomes of PD-L1-positive gastric carcinomas. Gastric Cancer 2020; epub ahead of print [PMID:
32206940 doi: 10.1007/s10120-020-01059-3]
74. Cerezo M, Guemiri R, Druillennec S, Girault I, Malka-Mahieu H, et al. Translational control of tumor immune escape via the eIF4F-
STAT1-PD-L1 axis in melanoma. Nat Med 2018;24:1877-86.
75. Jiang X, Zhou J, Giobbie-Hurder A, Wargo J, Hodi FS. The activation of MAPK in melanoma cells resistant to BRAF inhibition promotes
PD-L1 expression that is reversible by MEK and PI3K inhibition. Clin Cancer Res 2013;19:598-609.
76. Coelho MA, de Carné Trécesson S, Rana S, Zecchin D, Moore C, et al. Oncogenic RAS signaling promotes tumor immunoresistance by
stabilizing PD-L1 mRNA. Immunity 2017;47:1083-99.e6.
77. Seo AN, Kang BW, Bae HI, Kwon OK, Park KB, et al. Exon 9 mutation of PIK3CA associated with poor survival in patients with
Epstein-Barr virus-associated gastric cancer. Anticancer Res 2019;39:2145-54.
78. Song M, Chen D, Lu B, Wang C, Zhang J, et al. PTEN loss increases PD-L1 protein expression and affects the correlation between PD-
L1 expression and clinical parameters in colorectal cancer. PLoS One 2013;8:e65821.
79. Parsa AT, Waldron JS, Panner A, Crane CA, Parney IF, et al. Loss of tumor suppressor PTEN function increases B7-H1 expression and
immunoresistance in glioma. Nat Med 2007;13:84-8.
80. Kim YB, Ahn JM, Bae WJ, Sung CO, Lee D. Functional loss of ARID1A is tightly associated with high PD-L1 expression in gastric
cancer. Int J Cancer 2019;145:916-26.
81. Menyhárt O, Pongor LS, Győrffy B. Mutations defining patient cohorts with elevated PD-L1 expression in gastric cancer. Front
Pharmacol 2018;9:1522.
82. Mimura K, Teh JL, Okayama H, Shiraishi K, Kua LF, et al. PD-L1 expression is mainly regulated by interferon gamma associated with
JAK-STAT pathway in gastric cancer. Cancer Sci 2018;109:43-53.
83. Zhang Y, Liu W, Zhang W, Wang W, Song Y, et al. Constitutive activation of the canonical NF-κB signaling pathway in EBV-associated
gastric carcinoma. Virology 2019;532:1-10.
84. Shi Q, Zhang Y, Liu W, Xiao H, Qi Y, et al. Latent membrane protein 2A inhibits expression level of Smad2 through regulating miR-155-
5p in EBV-associated gastric cancer cell lines. J Med Virol 2020;92:96-106.
85. Iwakiri D, Minamitani T, Samanta M. Epstein-Barr virus latent membrane protein 2A contributes to anoikis resistance through ERK
activation. J Virol 2013;87:8227-34.
86. Qi YF, Liu M, Zhang Y, Liu W, Xiao H, et al. EBV down-regulates COX-2 expression via TRAF2 and ERK signal pathway in EBV-
associated gastric cancer. Virus Res 2019;272:197735.
87. Li H, Xia JQ, Zhu FS, Xi ZH, Pan CY, et al. LPS promotes the expression of PD-L1 in gastric cancer cells through NF-κB activation. J
Cell Biochem 2018;119:9997-10004.
88. Wang X, Wu WKK, Gao J, Li Z, Dong B, et al. Autophagy inhibition enhances PD-L1 expression in gastric cancer. J Exp Clin Cancer
Res 2019;38:140.
89. Xu D, Li J, Li RY, Lan T, Xiao C, et al. PD-L1 Expression is regulated by NF-κB during EMT signaling in gastric carcinoma. Onco
Targets Ther 2019;12:10099-105.
90. Hino R, Uozaki H, Murakami N, Ushiku T, Shinozaki A, et al. Activation of DNA methyltransferase 1 by EBV latent membrane protein
2A leads to promoter hypermethylation of PTEN gene in gastric carcinoma. Cancer Res 2009;69:2766-74.
91. Cai L, Ye Y, Jiang Q, Chen Y, Lyu X, et al. Epstein-Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating
PTEN-dependent pathways in nasopharyngeal carcinoma. Nat Commun 2015;6:7353.
92. Cai LM, Lyu XM, Luo WR, Cui XF, Ye YF, et al. EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma
cells by suppressing the tumor suppressor PTEN. Oncogene 2015;34:2156-66.
93. Moon JW, Kong SK, Kim BS, Kim HJ, Lim H, et al. IFNγ induces PD-L1 overexpression by JAK2/STAT1/IRF-1 signaling in EBV-
positive gastric carcinoma. Sci Rep 2017;7:17810.
94. Kawazoe A, Kuwata T, Kuboki Y, Shitara K, Nagatsuma AK, et al. Clinicopathological features of programmed death ligand 1 expression
with tumor-infiltrating lymphocyte, mismatch repair, and Epstein-Barr virus status in a large cohort of gastric cancer patients. Gastric
Cancer 2017;20:407-15.
95. Li Z, Lai Y, Sun L, Zhang X, Liu R, et al. PD-L1 expression is associated with massive lymphocyte infiltration and histology in gastric
cancer. Hum Pathol 2016;55:182-9.
96. Thompson ED, Zahurak M, Murphy A, Cornish T, Cuka N, et al. Patterns of PD-L1 expression and CD8 T cell infiltration in gastric
adenocarcinomas and associated immune stroma. Gut 2017;66:794-801.
97. Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, et al. Tumor necrosis factor receptor and Fas signaling
mechanisms. Annu Rev Immunol 1999;17:331-67.
98. Billiau A. Interferon-γ: biology and role in pathogenesis. Advances in Immunology Volume 62. Elsevier; 1996. pp. 61-130.
99. Jiang X, Wang J, Deng X, Xiong F, Ge J, et al. Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape. Mol
Cancer 2019;18:10.
100. Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, et al. Involvement of PD-L1 on tumor cells in the escape from host immune system and
tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A 2002;99:12293-7.
101. Lee SJ, Jang BC, Lee SW, Yang YI, Suh SI, et al. Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-
gamma-induced upregulation of B7-H1 (CD274). FEBS Lett 2006;580:755-62.
102. Bellucci R, Martin A, Bommarito D, Wang K, Hansen SH, et al. Interferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell