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Kepka. J Cancer Metastasis Treat 2019;5:53  I  http://dx.doi.org/10.20517/2394-4722.2018.114                                   Page 9 of 11

               of radiotherapy with chemotherapy should be further evaluated. It was demonstrated in a randomized trial
               that Atezolizumb added to standard chemotherapy with Carboplatin and Etoposide in ES SCLC improved
               overall survival, however patients with BM represented only 8.5% of the included cohort . Thus, further
                                                                                            [57]
               research is needed to investigate the role of immunotherapy in patients with BM from SCLC.


               DECLARATIONS
               Authors’ contributions
               The author solely contributed to the manuscript.

               Availability of data and materials
               Not applicable.

               Financial support and sponsorship
               None.

               Conflicts of interest
               All authors declared that there are no conflicts of interest.

               Ethical approval and consent to participate
               Not applicable.

               Consent for publication
               Not applicable.

               Copyright
               © The Author(s) 2019.



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