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Takeuchi et al. J Cancer Metastasis Treat 2018;4:38 Journal of Cancer
DOI: 10.20517/2394-4722.2017.83 Metastasis and Treatment

Review Open Access

Laparoscopic personalized function-preserving
gastrectomy with sentinel node mapping for early-

stage gastric cancer

Hiroya Takeuchi , Yuko Kitagawa 2
1,2
1 Department of Surgery, Hamamatsu University School of Medicine, Shizuoka 431-3192, Japan.
2 Department of Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.

Correspondence to: Dr. Hiroya Takeuchi, Department of Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama,
Higashi-ku, Hamamatsu-shi, Shizuoka 431-3192, Japan. E-mail: takeuchi@hama-med.ac.jp
How to cite this article: Takeuchi H, Kitagawa Y. Laparoscopic personalized function-preserving gastrectomy with sentinel node
mapping for early-stage gastric cancer. J Cancer Metastasis Treat 2018;4:38. http://dx.doi.org/10.20517/2394-4722.2017.83
Received: 12 Dec 2017 First Decision: 5 Feb 2018 Revised: 3 Jul 2018 Accepted: 9 Jul 2018 Published: 23 Jul 2018

Science Editor: Masayuki Watanabe Copy Editor: Jun-Yao Li Production Editor: Cai-Hong Wang

Abstract
Laparoscopic gastrectomy is considered as an indispensable option between endoscopic resection and standard
gastrectomy with open laparotomy for patients with early-stage gastric cancer. However, the extent of gastrectomy
and remnant gastric function may affect patients’ quality of life (QOL) after surgery. Therefore, function-preserving
gastrectomy in addition to laparoscopic surgery could be considered in patients with early-stage gastric cancer. A
prospective multicenter trial and meta-analyses of sentinel node (SN) mapping and biopsy for early-stage gastric cancer
have demonstrated favorable SN detection rates and accuracy of nodal metastatic status. Although a combination of
radioactive colloids with blue dyes as tracers is currently considered as the promising procedure of SN mapping in early-
stage gastric cancer, several new technologies, such as indocyanine green fluorescence imaging, may markedly improve
its accuracy. For early-stage gastric cancer, the development of laparoscopic personalized minimized gastrectomy with
SN mapping may help retain patents’ QOL after surgery. A recently developed full-thickness partial gastrectomy with
SN mapping and basin dissection would become a reliable minimally invasive gastrectomy for treating patients with cN0
early-stage gastric cancer.

Keywords: Sentinel node, gastric cancer, laparoscopic, nonexposed endoscopic wall-inversion surgery

INTRODUCTION
In East Asian countries, such as Japan and Korea, early-stage gastric cancer (cT1) is identified in many
patients owing to endoscopic diagnosis and surveillance . Nowadays endoscopic submucosal dissection
[1]
© The Author(s) 2018. Open Access This article is licensed under a Creative Commons Attribution 4.0
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