Page 965 - Read Online
P. 965

Brodosi et al. Hepatoma Res 2020;6:82  I  http://dx.doi.org/10.20517/2394-5079.2020.88                                        Page 9 of 11

                   2007;356:2457-71.
               27.  Lincoff AM, Wolski K, Nicholls SJ, Nissen SE. Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a
                   meta-analysis of randomized trials. JAMA 2007;298:1180-8.
               28.  Musso G, Cassader M, Paschetta E, Gambino R. Pioglitazone for advanced fibrosis in nonalcoholic steatohepatitis: New evidence, new
                   challenges. Hepatology 2017;65:1058-61.
               29.  Donadon V, Balbi M, Mas MD, Casarin P, Zanette G. Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with
                   chronic liver disease. Liver Int 2010;30:750-8.
               30.  Zhang ZJ, Zheng ZJ, Shi R, Su Q, Jiang Q, Kip KE. Metformin for liver cancer prevention in patients with type 2 diabetes: a systematic
                   review and meta-analysis. J Clin Endocrinol Metab 2012;97:2347-53.
               31.  Singh S, Singh PP, Singh AG, Murad MH, Sanchez W. Anti-diabetic medications and the risk of hepatocellular cancer: a systematic
                   review and meta-analysis. Am J Gastroenterol 2013;108:881-91; quiz 892.
               32.  Yu H, Zhong X, Gao P, et al. The potential effect of metformin on cancer: an umbrella review. Front Endocrinol (Lausanne) 2019;10:617.
               33.  Zhang X, Harmsen WS, Mettler TA, et al. Continuation of metformin use after a diagnosis of cirrhosis significantly improves survival of
                   patients with diabetes. Hepatology 2014;60:2008-16.
               34.  Hauner H. The mode of action of thiazolidinediones. Diabetes Metab Res Rev 2002;18:S10-5.
               35.  Hauner H. The mode of action of thiazolidinediones. Diabetes Metab Res Rev 2002;18:S10-5.
               36.  Belfort R, Harrison SA, Brown K, Darland C, Finch J, et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic
                   steatohepatitis. N Engl J Med 2006;355:2297-307.
               37.  Belfort R, Harrison SA, Brown K. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med
                   2006;355:2297-307.
               38.  Chalasani NP, Sanyal AJ, Kowdley KV, et al. Pioglitazone versus vitamin E versus placebo for the treatment of non-diabetic patients with
                   non-alcoholic steatohepatitis: PIVENS trial design. Contemp Clin Trials 2009;30:88-96.
               39.  Promrat K, Lutchman G, Uwaifo GI, et al. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology
                   2004;39:188-96.
               40.  Sanyal AJ, Chalasani N, Kowdley KV, et al; NASH CRN. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J
                   Med 2010;362:1675-85.
               41.  Musso G, Cassader M, Paschetta E, Gambino R. Thiazolidinediones and advanced liver fibrosis in nonalcoholic steatohepatitis: a meta-
                   analysis. JAMA Intern Med 2017;177:633-40.
               42.  Dormandy JA, Charbonnel B, Eckland DJ, et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in
                   the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet
                   2005;366:1279-89.
               43.  Kernan WN, Viscoli CM, Furie KL, et al; IRIS Trial Investigators. Pioglitazone after ischemic stroke or transient ischemic attack. N Engl
                   J Med 2016;374:1321-31.
               44.  Chang CH, Lin JW, Wu LC, Lai MS, Chuang LM, Chan KA. Association of thiazolidinediones with liver cancer and colorectal cancer in
                   type 2 diabetes mellitus. Hepatology 2012;55:1462-72.
               45.  Bril F, Lomonaco R, Kalavalapalli S, Lai J, Cusi K. 223-OR: Pioglitazone discontinuation in patients with nonalcoholic steatohepatitis
                   (NASH) is associated with disease recurrence. Diabetes 2019;68:223-OR.
               46.  Motola D, Piccinni C, Biagi C, et al. Cardiovascular, ocular and bone adverse reactions associated with thiazolidinediones: a
                   disproportionality analysis of the US FDA adverse event reporting system database. Drug Saf 2012;35:315-23.
               47.  Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2
                   diabetes. Lancet 2006;368:1696-705.
               48.  Carbone LJ, Angus PW, Yeomans ND. Incretin-based therapies for the treatment of non-alcoholic fatty liver disease: a systematic review
                   and meta-analysis. J Gastroenterol Hepatol 2016;31:23-31.
               49.  Yilmaz Y, Yonal O, Deyneli O, Celikel CA, Kalayci C, Duman DG. Effects of sitagliptin in diabetic patients with nonalcoholic
                   steatohepatitis. Acta Gastroenterol Belg 2012;75:240-4.
               50.  Kanazawa I, Tanaka K, Sugimoto T. DPP-4 inhibitors improve liver dysfunction in type 2 diabetes mellitus. Med Sci Monit
                   2014;20:1662-7.
               51.  Alam S, Ghosh J, Mustafa G, Kamal M, Ahmad N. Effect of sitagliptin on hepatic histological activity and fibrosis of nonalcoholic
                   steatohepatitis patients: a 1-year randomized control trial. Hepat Med 2018;10:23-31.
               52.  Cui J, Philo L, Nguyen P, et al. Sitagliptin vs. placebo for non-alcoholic fatty liver disease: a randomized controlled trial. J Hepatol
                   2016;65:369-76.
               53.  Smits MM, Tonneijck L, Muskiet MH, et al. Twelve week liraglutide or sitagliptin does not affect hepatic fat in type 2 diabetes: a
                   randomised placebo-controlled trial. Diabetologia 2016;59:2588-93.
               54.  Brown E, Cuthbertson DJ, Wilding JP. Newer GLP-1 receptor agonists and obesity-diabetes. Peptides 2018;100:61-7.
               55.  Armstrong MJ, Houlihan DD, Rowe IA, et al. Safety and efficacy of liraglutide in patients with type 2 diabetes and elevated liver
                   enzymes: individual patient data meta-analysis of the LEAD program. Aliment Pharmacol Ther 2013;37:234-42.
               56.  Eguchi Y, Kitajima Y, Hyogo H, et al; Japan Study Group for NAFLD (JSG-NAFLD). Pilot study of liraglutide effects in non-alcoholic
                   steatohepatitis and non-alcoholic fatty liver disease with glucose intolerance in Japanese patients (LEAN-J). Hepatol Res 2015;45:269-78.
               57.  Armstrong MJ, Gaunt P, Aithal GP, et al. Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a
                   multicentre, double-blind, randomised, placebo-controlled phase 2 study. The Lancet 2016;387:679-90.
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