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Otsuka et al.                                                                                                                                   Indications and technique for LLR in HCC with liver cirrhosis

           may be indicated, with or without prior local ablation   Conflicts of interest
           therapy, if abdominal  adhesion  is limited  and  tumor   There are no conflicts of interest.
           location  and characteristics  are suitable  for a
           laparoscopic approach. [57]                        Patient consent
                                                              Not involved.
           Long-term outcomes
           With respect to oncological considerations, evidence from   Ethics approval
           meta-analyses suggests that surgical tumor margins are   Not involved.
           adequately maintained during LLR. [46,47,50-54]  In addition, an
           analysis of long-term outcomes showed no oncological   REFERENCES
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