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Igarashi et al. Hepatoma Res 2022;8:21 https://dx.doi.org/10.20517/2394-5079.2022.02 Page 5 of 6

Figure 3. Third operation: (A) preoperative 3D CT reconstruction; (B) Glissonean approach respecting Laennec’s capsule with isolation
of Glissonean branches of Segment 2 (G2); (C) intraoperative ultrasonography (IOUS); (D) HCC staining by ICG; (E) isolation of left
hepatic vein (LHV) as drainage vein of Segment 2; (F) surgical field after LAR of Segment 2; and (G) macroscopic findings and
micropathological results. 3D CT, three-dimensional computed tomography; HCC, hepatocellular carcinoma; ICG, Indocyanine green;
LAR, laparoscopic anatomical liver resection.

significance and advancements in subsegmentectomy and cone unit resection, in the future.

DECLARATIONS
Authors’ contributions
Conceived and designed the manuscript: Go Wakabayashi
Wrote the manuscript: Kazuharu Igarashi
Critically revised the manuscript: Go Wakabayashi, Kohei Mishima, Takahiro Ozaki

Availability of data and materials
Data supporting our Report are deposited in our database and are available at request via contat with our
corresponding author.

Financial support and sponsorship
None.

Conflict of interest
All authors declared that there no conflicts of interest.