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Sioutas et al. Hepatoma Res 2020;6:4 I http://dx.doi.org/10.20517/2394-5079.2019.43 Page 7 of 9

morbidity, mortality, and LOS after liver resection. However, deducing meaningful conclusions remains
challenging due to the lack of consensus regarding frailty definition, assessment tools, and score cutoffs.
Future studies should focus on performing between-tool comparisons, developing a hepatectomy-
specific frailty assessment tool, and evaluating the role of frailty assessment tools in preoperative patient
optimization.

DECLARATIONS
Authors’ contributions
Study concept, data analysis and interpretation, critical revision of the manuscript, final approval of the
manuscript: Ziogas IA, Sioutas GS, Tsoulfas G
Data acquisition, drafting of the manuscript: Sioutas GS, Ziogas IA

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2020.

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