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Page 12 of 14 Moriguchi et al. Hepatoma Res 2019;5:43 I http://dx.doi.org/10.20517/2394-5079.2019.20

62. Hashimoto E, Tokushige K. Prevalence, gender, ethnic variations, and prognosis of NASH. J Gastroenterol 2011;46 (Suppl 1):63-9.
63. Hossain N, Afendy A, Stepanova M, Nader F, Srishord M, et al. Independent predictors of fibrosis in patients with nonalcoholic fatty
liver disease. Clin Gastroenterol Hepatol 2009;7:1224-9.
64. Tarantino G, Conca P, Riccio A, Tarantino M, di Minno MN, et al. Enhanced serum concentrations of transforming growth factor-β1
in simple fatty liver: is it really benign? J Transl Med 2008;6:72.
65. Adams LA, Lymp JF, Sauver JS, Sanderson SO, Lindor KD, et al. The natural history of nonalcoholic fatty liver disease: a population-
based cohort study. Gastroenterology 2005;129:113-21.
66. Lomonaco R, Ortiz-Lopez C, Orsak B, Finch J, Webb A, et al. Role of ethnicity in overweight and obese patients with nonalcoholic
steatohepatitis. Hepatology 2011;54:837-45.
67. Bambha K, Belt P, Abraham M, Wilson LA, Pabst M, et al. Ethnicity and nonalcoholic fatty liver disease. Hepatology 2012;55:769-80.
68. Chang ET, Yang J, Alfaro-Velcamp T, So SK, Glaser SL, et al. Disparities in liver cancer incidence by nativity, acculturation, and
socioeconomic status in California Hispanics and Asians. Cancer Epidemiol. Biomarkers Prev 2010;19:3106-18.
69. Speliotes EK, Butler JL, Palmer CD, Voight BF; GIANT Consortium; MIGen Consortium; NASH CRN, Hirschhorn JN. PNPLA3
variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease. Hepatology
2010;52:904-12.
70. Singal AG, Manjunath H, Yopp AC, Beg MS, Marrero JA, et al. The effect of PNPLA3 on fibrosis progression and development of
hepatocellular carcinoma: a meta-analysis. Am J Gastroenterol 2014;109:325-34.
71. Krawczyk M, Stokes CS, Romeo S, Lammert F. HCC and liver disease risks in homozygous PNPLA3 p.I148M carriers approach
monogenic inheritance. J Hepatol 2015;62:980-1.
72. Ye Q, Qian BX, Yin WL, Wang FM, Han T. Association between the HFE C282Y, H63D polymorphisms and the risks of non-
alcoholic fatty liver disease, liver cirrhosis and hepatocellular carcinoma: an updated systematic review and meta-analysis of 5,758
cases and 14,741 controls. PLoS One 2016;11:e0163423.
73. Donati B, Dongiovanni P, Romeo S, Meroni M, McCain M, et al. MBOAT7 rs641738 variant and hepatocellular carcinoma in non-
cirrhotic individuals. Sci Rep 2017;7:4492.
74. Piscaglia F, Svegliati-Baroni G, Barchetti A, Pecorelli A, Marinelli S, et al. Clinical patterns of hepatocellular carcinoma in
nonalcoholic fatty liver disease: a multicenter prospective study. Hepatology 2016;63:827-38.
75. Sorrentino P, D’Angelo S, Ferbo U, Micheli P, Bracigliano A, et al. Liver iron excess in patients with hepatocellular carcinoma
developed on non-alcoholic steato-hepatitis. J Hepatol 2009;50:351-7.
76. Nelson JE, Wilson L, Brunt EM, Yeh MM, Kleiner DE, et al.; Nonalcoholic Steatohepatitis Clinical Research Network. Relationship
between the pattern of hepatic iron deposition and histological severity in nonalcoholic fatty liver disease. Hepatology 2011;53:448-57.
77. White DL, Kanwal F, El-Serag HB. Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on
systematic review. Clin Gastroenterol Hepatol 2012;10:1342-59.
78. Kim GA, Lee HC, Choe J, Kim MJ, Lee MJ, et al. Association between non-alcoholic fatty liver disease and cancer incidence rate. J
Hepatol 2018;68:140-6.
79. Colombo M, de Franchis R, Del Ninno E, Sangiovanni A, De Fazio C, et al. Hepatocellular carcinoma in Italian patients with cirrhosis.
N Engl J Med 1991;325:675-80.
80. Bugianesi E. Nonalcoholic steatohepatitis and cancer. Clin Liver Dis 2007;11:191-207.
81. Bosch FX, Ribes J, Cleries R, Diaz M. Epidemiology of hepatocellular carcinoma. Clin Liv Dis 2005;9:191-211.
82. Marrero JA, Fontana RJ, Su GL, Conjeevaram HS, Emick DM, et al. NAFLD may be a common underlying liver disease in patients
with hepatocellular carcinoma in the United States. Hepatology 2002;36:1349-54.
83. Bugianesi E, Leone N, Vanni E, Marchesini G, Brunello F, et al. Expanding the natural history of nonalcoholic steatohepatitis: from
cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology 2002;123:134-40.
84. Caldwell SH, Oelsner DH, Iezzoni JC, Hespenheide EE, Battle EH, et al. Cryptogenic cirrhosis: clinical characterization and risk
factors for underlying disease. Hepatology 1999;29:664-9.
85. Kojima H, Sakurai S, Matsumura M, Umemoto N, Uemura M, et al. Cryptogenic cirrhosis in the region where obesity is not prevalent.
World J Gastroenterol 2006;12:2080-5.
86. Poonawala A, Nair SP, Thuluvath PJ. Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case-control study.
Hepatology 2000;32:689-92.
87. Ertle J, Dechene A, Sowa JP, Penndorf V, Herzer K, et al. Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in
the absence of apparent cirrhosis. Int J Cancer 2011;128:2436-43.
88. Paradis V, Zalinski S, Chelbi E, Guedj N, Degos F, et al. Hepatocellular carcinomas in patients with metabolic syndrome often develop
without significant liver fibrosis: a pathological analysis. Hepatology 2009;49:851-9.
89. Liu TC, Vachharajani N, Chapman WC, Brunt EM. Noncirrhotic hepatocellular carcinoma: derivation from hepatocellular adenoma?
Clinicopathologic analysis. Mod Pathol 2014;27:420-32.
90. Baffy G, Brunt EM, Caldwell SH. Hepatocellular carcinoma in nonalcoholic fatty liver disease: an emerging menace. J Hepatol
2012;56:1384-91.
91. Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection.
Hepatology 2010;1:1820-32.
92. Mittal S, El-Serag HB, Sada YH, Kanwal F, Duan Z, et al. Hepatocellular carcinoma in the absence of cirrhosis in United States
veterans is associated with nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 2016;14:124-31.