Page 68 - Read Online

Page 322 Meyer et al. Cancer Drug Resist 2019;2:313-25 I http://dx.doi.org/10.20517/cdr.2019.11

Relapsed solid
Vorinostat in children tumors, lymphoma, Phase 1 Completed
(NCT01422499)
or leukemia
Vorinostat with or
without isotretinoin in
treating young patients Relapsed solid
with recurrent or tumors, lymphoma, Phase 1 Completed
refractory solid tumors, or leukemia
lymphoma, or leukemia
(NCT00217412)
Total therapy for
infants with acute Acute lymphoblastic
lymphoblastic leukemia leukemia Phase 1/2 Recruiting
(NCT02553460)
Total therapy XVII
for newly diagnosed Acute lymphoblastic
patients with acute leukemia Phase Recruiting
lymphoblastic leukemia Acute lymphoblastic 2/3
and lymphoma lymphoma
(NCT03117751)
Acute lymphoblastic
A pilot study of leukemia
decitabine and Precursor B-cell
vorinostat with lymphoblastic
chemotherapy leukemia Phase 1/2 Terminated
for relapsed ALL Precursor T-cell
(NCT01483690) lymphoblastic
leukemia
Bortezomib and Mixed lineage acute
Vorinostat vorinostat in younger leukemia
patients with refractory Acute myeloid
or relapsed MLL leukemia Phase 2 Terminated
rearranged hematologic Acute lymphoid
malignancies leukemia
(NCT02419755)
Histone detacetylase Acute lymphoblastic
inhibitors Fludarabine phosphate, leukemia – recurrent
clofarabine, and busulfan or in remission
with vorinostat in Acute myeloid
treating patients with leukemia – recurrent
acute leukemia in or in remission Phase 1 Active, not
remission or relapse Allogeneic recruiting
undergoing donor hematopoietic stem
stem cell transplant cell transplantation
(NCT02083250) Myelodysplastic
syndrome
Bortezomib, vorinostat,
and dexamethasone
for relapsed/ Acute lymphoblastic Phase 2 Terminated
refractory acute leukemia
lymphoblastic leukemia
(NCT01312818)
Pre-reinductive
decitabine and
vorinostat in relapsed Acute lymphoblastic
lymphoblastic lymphoma Phase 2 Terminated
lymphoma or acute Acute lymphoblastic
lymphoblastic leukemia leukemia
(NCT00882206)
Lymphoblastic
A study of panobinostat leukemia
in children with Myelogenous
refractory hematologic leukemia Phase 1/2 Completed
malignancies Hodgkin’s disease
Panobinostat (NCT01321346) non-Hodgkin’s
lymphoma
Re-induction therapy for
relapsed pediatric T-cell Acute lymphoblastic
acute lymphoblastic leukemia Phase 2 Terminated
leukemia or lymphoma Non-Hodgkin’s
(NCT02518750) lymphoma