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PREFACE

Pharmacogenetics and pharmacogenomics have expanded rapidly over the past years and they are the basis of personalized
medicine. The pharmacological treatment of cancer is an ideal field for the application of pharmacogenetics into clinical
practice. Testing of patients for genetic markers of efficacy or toxicity of anticancer therapy is increasingly being used as
a result of clinical studies based on genotype stratification, availability of approved clinical tests and of an always more
robust clinical pharmacogenetic information, and guidelines.

This special issue of Cancer Drug Resistance is designed to provide an overview of the role of pharmacogenetics and
pharmacogenomics in cancer treatment, including methods of discovery and clinical drug development, available
information on drug labels, web resources, and guidelines, with particular regard to specific cancer drug classes. Finally,
the integration of somatic pharmacogenomic markers into clinical practice with examples of main cancer types is also
addressed.

Enrico Mini
Stefania Nobili
Special Issue Editors