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            Special Issue
            Targeted cancer therapy



            Guest Editors:
                                              Special Issue Introduction
            Dr. Elisa Giovannetti,            Targeted therapies in cancer aim to specically block the activity of
            MD, PhD                           crucial proteins or signaling pathways necessary for the growth and/or
            Lab Medical Oncology, VU          survival of tumor cells. A major breakthrough in targeted cancer
            University Medical Center         therapy was the introduction nearly two decades ago of imatinib, an
            (Vumc), Cancer Center             inhibitor of the BCR-ABL tyrosine kinase for the treatment of chronic
            Amsterdam, the                    myeloid leukemia. Over the last years, signicant advances in our
            Netherlands.                      understanding of tumor biology have facilitated the development of
            Cancer Pharmacology Lab,          many drugs targeting not only kinases, but also other protein families
            AIRC Start-Up Unit, University    and cellular processes. Several of these agents are currently employed
            of Pisa, Italy.                   or being implemented for the treatment of different hematologic and
            Email:                            solid malignancies, such as lung cancer.
            elisa.giovannetti@gmail.com       The special issue on “Targeted cancer therapy” will include Reviews
                                              and Commentaries updating the clinical use of targeted agents in the
            Dr. Jose Antonio                  treatment of different tumor types, and the mechanisms that underlie
                                              the action of drugs directed to different types of targets. The special
            Rodriguez, PhD
                                              issue will also include Research articles presenting novel outstanding
            Department of Genetics,
                                              data on all aspects of targeted cancer therapy. All submissions will
            Physical Anthropology and
                                              undergo rigorous peer revision and will be published free of charge
            Animal Physiology (School of
                                              upon acceptance.
            Medicine and Nursing) of
            the University of the Basque
                                                Benets
            Country (UPV/EHU), Basque
                                                Rigorous mechanism in peer review: one manuscript must be
            Country, Spain.
                                                reviewed by at least two relevant experts. We will endeavour to
            Email:
                                                ensure high standards for the review process and subsequent
            josean.rodriguez@ehu.es
                                                publication by a team of efcient and professional reviewers and
                                                scientic editors.
                                                No publication fee: there would be absolutely no charge for
                                                publication.
                                                Rapid publication: we will ensure that accepted papers will be
                                                published in a short processing time (the average processing time:
                                                50.7 days) with a high quality.
                                                Open Access: As an author you will retain the copyright to your work.
                                                By licensing your work under the Creative Commons Attribution
                                                License, articles can be re-used and re-distributed without restriction,
                                                as long as the original work is correctly cited.
                                                Wide promotions: Published articles will be promoted at academic
                                                conferences, through social networks for scientists and relevant
                                                indexing services.


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                                              Tel:+1 323 9987086;E-mail:editorial@cdrjournal.com  /special_issues
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