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Naik et al. Vessel Plus 2018;2:38  I  http://dx.doi.org/10.20517/2574-1209.2018.62                                                        Page 7 of 10

                                           Odds ratio                             Odds ratio
                 Study or subgroup  Weight IV, random, 95% CI                  IV, random, 95% CI
                 1.1.1 RCT
                 Nowicki; 2011     8.3%    0.11 [0.01, 2.01]
                 Rudez; 2007       53.8%   0.37 [0.12, 1.17]
                 Shapira; 2006               Not estimable
                 Subtotal (95% CI)  62.2%  0.31 [0.11, 0.92]
                 Total events
                               2
                                                         2
                                      2
                 Heterogeneity: Tau  = 0.00; χ  = 0.60, df = 1 (P = 0.44); I  = 0%
                 Test for overall effect: Z = 2.12 (P = 0.03)
                 1.1.2 Matched
                 Bisleri; 2016     8.6%    0.07 [0.00, 1.29]
                 Navia; 2011       29.3%   0.58 [0.12, 2.76]
                 Subtotal (95% CI)  37.8%  0.29 [0.04, 2.00]
                 Total events
                               2
                                      2
                                                         2
                 Heterogeneity: Tau  = 0.78; χ  = 1.56, df = 1 (P = 0.21); I  = 36%
                 Test for overall effect: Z = 1.25 (P = 0.21)
                 Total (95% CI)    100.0%  0.33 [0.14, 0.77]
                 Total events
                                      2
                                                         2
                 Heterogeneity: Tau  = 0.00; χ  = 2.18, df = 3 (P = 0.54); I  = 0%
                               2
                                                                              0.1
                                                                                             10
                 Test for overall effect: Z = 2.57 (P = 0.01)        0.005  Favours [ERAH]  1 Favours [ORAH]  200
                                       2
                 Test for subgroup differences: χ  = 0.00, df = 1 (P = 0.95); I  = 0%
                                                          2
               Figure 2. Forest plot of wound infection in endoscopic radial artery harvest (ERAH) vs. open radial artery harvest (ORAH)
               The RA offers a decreased risk of atherosclerosis and post-operative complications compared to other graft
               options like venous grafts. ORAH has a higher risk of wound infection with a larger scar but a shorter
               harvest time and is easier to learn. ERAH is feasible in all patients when performed by skillful personnel,
               has fewer arm complications, and provides a higher patient satisfaction with better cosmetic results but
               takes a longer time to perform when compared to ORAH [58,59]  The post-operative cardiac complications and
               outcomes remain comparable in the two approaches.


               DECLARATIONS
               Authors’ contributions
               Wrote the paper, created figures for paper: Naik A
               Idea generation, helped in writing: Rahouma M
               Author for different parts of paper: Rahouma M, Spadaccio C, Khan F
               Reviewed and edited of paper: Spadaccio C, Mehta K, Baudo M, Kamel M, Khan F, Hameed I, Wingo M,
               Ruan Y, Abouarab A, Hossny M, Girardi LN, Gaudino M
               Helped with review of figures and tables: Mehta K
               Made table for paper: Baudo M

               Availability of data and materials
               Data and materials used to help write this article are available for public access.

               Financial support and sponsorship
               None.


               Conflicts of interest
               All authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               Not applicable.
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