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               significant advances on the horizon.


               DECLARATIONS
               Authors’ contributions
               Contributed to the writing of this review paper: Shah RJ, Pan S, Lanier GM, Mellela L, Aronow WS, Jain D


               Availability of data and materials
               Not applicable.

               Financial support and sponsorship
               None.

               Conflict of interest
               All authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               Not applicable.

               Consent for publication
               Not applicable.


               Copyright
               © The Author(s) 2021.


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