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Madiedo et al. Plast Aesthet Res 2018;5:40  I  http://dx.doi.org/10.20517/2347-9264.2018.40                                        Page 5 of 10

                                 Table 1. Socio-demographic variables and clinical characteristics of burns
                                Variables                       Frequency   Percentage
                                Male                              96           70
                                Female                            42           30
                                Injury mechanism
                                  Flame                           55           40
                                  Electricity                     19           13.7
                                  Scald                           17           12.3
                                  Deep partial-thickness burn     52           37.7
                                  Full-thickness burn             28           20.3
                                  Mixed burn (deep partial- and full-thickness)  29  21
                                                                  Median       Range
                                Age                               24.5         7-74
                                Burned body surface area          24.34        2-66

               The mean extension of total compromised body surface area was 24.34% (range: 2%-66%). Concerning burn
               depth, 52 (37.7%) patients exhibited partial-thickness burns, 28 (20.3%) patients showed full-thickness burns,
               and 29 (21%) patients had mixed burns, i.e., both deep partial- and full-thickness burns. The most common
               compromised anatomical areas were the upper limbs accounting for 77.4% (n = 89), face 46% (n = 53), trunk
               40% (n = 46), lower limbs 39.1% (n = 45), and neck 21% (n = 29). Mean hospital stay consisted of 16 days (range:
               8-100 days).

               Among the 138 patients, 106 (76.8%) patients underwent a single early eschar removal procedure by tangential
               excision, 19 (13.7%) patients required 2 escharectomies, 6 (4.3%) patients 3 escharectomies, and 7 (5.0%) patients
               4 escharectomies. Patients having full-thickness burns underwent more escharectomies. In 26 (18.8%) patients,
               the escharectomy area was covered temporarily with skin allografts prior to carrying out the definitive
               coverage with split-thickness skin autografts, as to promote the formation of granulation tissue suitable for
               grafts.


               In all, 46 (33.3%) patients required several grafting sessions, involving 2-5 additional procedures. These
               subjects exhibited burns > 20% of extension, full-thickness burns, and limited donor sites. Ten (7.2%) of the 138
               patients developed infection, resulting in full or partial graft failure. Reported cultures included Acinetobacter
               baumannii (n = 4, 2.9%), Pseudomonas aeruginosa (n = 4, 2.9%), and Klebsiella pneumoniae (n = 2, 1.4%). No
               case of mortality was reported. Initial scars were assessed at first postoperative month, and definitive outcomes
               were determined at month 12 based on the VSS.


               Of the 138 patients, 130 (94.2%) showed mild scars (score ≤ 3 in VSS). These were flat and had a similar
               appearance to normal skin; they were supple and elastic, and had a few elements of pigmentation
               (hypopigmentation and hyperpigmentation) or vascularization (pink) [Figures 3-6]. Four (2.9%) patients
               showed moderate scars (score 4-7) having a < 5 mm thickness and width, and a < 2 mm height. There were
               some changes in pigmentation and vascularization (pink to slight red); nonetheless, there was yielding and no
               evidence of rigidity or functional limitations, although some developed fragile areas with low resistance. Four
               (2.9%) patients showed severe scars (score ≥ 8) having clear signs of hypertrophy or keloid at 12-month follow-
               up. There was some degree of contracture and functional limitations, particularly in flexion creases sites.
               These 4 (2.9%) patients developed infection in the grafted areas, and they required surgical correction through
               contracture release and the application of new grafts [Table 2].

               In terms of rehabilitation, upon admission, all patients had developed some degree of edema in their upper
               and lower limbs. They also reported pain as per visual analog scale (VAS) at rest, which increased during
               muscle activity. Functional joint limitation was directly associated with skin involvement of finger and wrist
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