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Gaviria et al. Plast Aesthet Res 2018;5:35  I  http://dx.doi.org/10.20517/2347-9264.2018.38                                            Page 5 of 7

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               Figure 1. A: A 25-year-old woman, who suffered thermal burn caused by alcohol, with a deep partial- and full-thickness burn covering
               30% TBSA. There were injuries to the face, neck, anterior chest, and upper limbs. She presented severe mentocervical contracture; B: the
               photograph shows the area following excision of the scar; C: the single-layer dermal matrix is shown in place; D: the split-thickness skin
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               graft may be observed over the template; E: outcome at 12 months postoperatively after reconstruction with 135 cm  of acellular dermal
               matrix and autografts in a single-step procedure, without functional limitations; F: pinch test exhibiting pliability of the reconstructed skin.
               TBSA: total body surface area


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               Figure 2. A: A 38-year-old woman, who suffered thermal burn caused by mineral spirits, with full-thickness burns that developed in
               multiple keloid scars in the mentocervical region; B: defect after excision of keloid scars; C: the photograph shows the application of the
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               single-layer dermal matrix over the defect; D: result after placing 206 cm  of dermal regeneration matrix and autografts in a single-step
               procedure; E: Appearance at 10 months postoperatively. She did not present any functional limitations

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               Figure 3. A: A 38-year-old woman, who suffered thermal burn caused by alcohol, with a full-thickness burn covering 30% TBSA; B:
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               injured area after eschar removal; C: reconstruction with 210 cm  of dermal matrix and autografts. She presented 5-cm  graft loss that
               was treated with autologous keratinocyte cultures; D: the picture shows the appearance at 9 months postoperatively. TBSA: total body
               surface area
               Recently, there has been an increased number of reports describing the use of several skin substitutes as a
               good reconstruction alternative. Some of them, such as Glyaderm, Integra® bilayer, and biodegradable poly-
               urethane dermal substitute, require a two-stage procedure consisting initially of a dermal matrix implanta-
                                                                                          [9]
               tion and subsequently of skin grafting once there is complete take of the matrix. Seo et al.  show a report of
               24 neck reconstructions with a 95.9% take rate, under the use of AlloDerm and Matriderm, by placing the
               skin graft immediately after the dermal matrix implantation in a single-stage procedure.
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