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Mataix et al. Plast Aesthet Res 2020;7:69 Plastic and
DOI: 10.20517/2347-9264.2020.138 Aesthetic Research

Review Open Access

Deschampsia antarctica extract (Edafence ) as
®
a powerful skin protection tool against the aging

exposome

Manuel Mataix *, Azahara Rodríguez-Luna , María Gutiérrez-Pérez , Massimo Milani , Alberto
1,
3
2
1
Gandarillas , Jesús Espada , Azahara Pérez-Davó *
7,
5,6
4
1 Department of Biology, Faculty of Sciences, Autónoma University of Madrid (UAM), Instituto Ramón y Cajal de Investigación
Sanitaria (IRYCIS), Madrid 28049, Spain.
2 Innovation and Development, Cantabria Labs, Madrid 28043, Spain.
3 Medical Department, Cantabria Labs Difa Cooper, Caronno Pertusella, VA 21042, Italy.
4 Cell Cycle, Stem Cell Fate and Cancer Laboratory, Institute for Research Marqués de Valdecilla (IDIVAL), Santander 39011, Spain.
5 Experimental Dermatology and Skin Biology Group, Ramón y Cajal Institute for Health Research, Ramón y Cajal University
Hospital, Madrid 28034, Spain.
6 Centro Integrativo de Biología y Química Aplicada (CIBQA), Universidad Bernardo O’Higgins, Santiago 8370993, Chile.
7 Medical Affairs Department, Cantabria Labs, Madrid 28043, Spain.
*These authors contributed equally to this work.
Correspondence to: Dr. Azahara Rodríguez-Luna, Innovation and Development, Cantabria Labs, Calle Arequipa 1, Madrid
28043, Spain. E-mail: azahara.rodriguez@cantabrialabs.es; Dr. Azahara Pérez-Davó, Medical Affairs Department, Cantabria
Labs, Calle Arequipa 1, Madrid 28043, Spain. E-mail: azahara.perez@cantabrialabs.es
How to cite this article: Mataix M, Rodríguez-Luna A, Gutiérrez-Pérez M, Milani M, Gandarillas A, Espada J, Pérez-Davó A.
Deschampsia antarctica extract (Edafence®) as a powerful skin protection tool against the aging exposome. Plast Aesthet Res
2020;7:69. http://dx.doi.org/10.20517/2347-9264.2020.138

Received: 25 Jun 2020 First Decision: 9 Oct 2020 Revised: 27 Oct 2020 Accepted: 10 Nov 2020 Published: 5 Dec 2020
Academic Editor: Salvador Gonzalez, Raúl González-García Copy Editor: Cai-Hong Wang Production Editor: Jing Yu

Abstract
The impact of the interaction of all combined environmental agents to which an individual is exposed during
his/her lifetime, as well as how his/her organism responds to these influences, defines health, aging, and
disease. The systematic, integrative characterization of the different elements making up the “exposome” is thus
necessary to identify and exploit the potential of compounds capable of conferring protection with minimal side
effects. Extracts from the natural world, containing synergistic combinations of compounds with antioxidant and
protective properties, have long been used in traditional medicine. Modern science has the opportunity to leverage
these substances honed by evolution and use them safely and reliably, with a profound mechanistic knowledge
and guaranteeing standardization and absence of toxicity. Here, we discuss our current knowledge regarding the
potential of a soluble extract of the hair grass Deschampsia antarctica (as its standardized commercial preparation
Edafence®) to counteract the skin exposome and its impact on skin aging and disease.

© The Author(s) 2020. Open Access This article is licensed under a Creative Commons Attribution 4.0
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