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Lies et al. Plast Aesthet Res 2019;6:18  I  http://dx.doi.org/10.20517/2347-9264.2019.27                                                 Page 5 of 9

               Table 1. Overview of articles
               Author        Adani et al. [26,27]     Koul et al. [33]  Ulusal et al. [19]  Sundine et al. [24]  Scheker et al. [25]  Al-Qattan [29]  Lu et al. [17]
               # of Patients  12        8              8         14          9          4         6
               Type of Surgery  single composite, single, 7 free flap with  single lateral   7 staged vs. 7   single tendon graftstaged, groin  single,
                             7 dorsalis pedis  palmaris longus graft, 1  arm composite  single  flaps  posterior
                             free flap, 5 radial  posterior interosseous  free flap triceps       interosseous
                             forearm island   artery with palmaris                                artery
                             flap       longus graft
               Average Patient Age 33   29             32        25 vs. 33   38         21        No Data
               Average Time to   14 days  2.3 days     11 days   No Data     Within 24 hours 7 months  No Data
               Surgery Post-Injury
               ROM           full MP ROM stiff 192 at 8 weeks, 237 at  No Data  51 vs. 56  48  Average 82  No Data
                             IPJ case 2  12 weeks, combined
                                        268 at 12 weeks, 274 at
                                        6 months
               Complications  tenolysis 1/12,   no extension lag  two rays, three  None  2 complications  None  no tenolysis
                             hypertrophic scar,        tenolysis             recorded
                             donor partial skin
                             graft loss 6/12
               Grip Strength  No Data   average 54 at 12 weeks No Data  Average 50% vs.  Average 60%  No Data  No Data
                                                                 53%
               Follow-up Timing  No Data  No Data      15 months  No Data    No Data    8 months  No Data
               Time to Max ROM  No Data  No Data       No Data   630 vs. 214 days 3 months  430 days  No Data
               % Returned to Work No Data  No Data     No Data   43 vs. 86   89         No Data   No Data
               Average # of   1.33      1              1.75      6 vs. 2     1.22       4         No Data
               Operations

               ROM: range of motion

               Table 2. Comparison of surgical outcomes
               Flap Type °  MP TAM (°)  Days to Max ROM  Grip Strength  Complication rate  # Operations  Return to work
                           (P = 0.3123)  *(P < 0.001)  (P = 0.2713)  *(P < 0.001)  *(P < 0.001)  *(P = 0.0381)
               Immediate n 50  56.99  213.86         57%         36%            1.45        88%
               Staged n 11  61.39     551.18         50%         0%             5.18        43%
               °           *(P = 0.0067)  (P = 0.1610)  °        (P = 0.4740)   (P = 0.0604)  °
               Pedicled n 16  75.25   522.4          NR          30%            3.4         NR
               Free n 45   55.4       380.62         NR          29%            1.93        NR

               ROM: range of motion;  : number of operations; *: P < 0.05 considered significant; TAM: total active motion; NR: not recorded
                               #
               to be initiated earlier. Scheker et al.  reported better function with primary reconstruction, with fewer
                                              [25]
               operations, a shorter hospital stay, minimal complications, and a shorter period of disability. Adani et al. [26,27]
               reviewed completely vascularized single stage reconstruction using dorsalis pedis and radial forearm
               cutaneoutendinous flaps. Our study confirmed that there is significantly less operations required, an earlier
               return to maximum ROM, and greater chance of returning to work; in contrast to some reports, there was
               no significant difference in total active motion and significantly more complications reported in immediate
               reconstruction. Obvious advantages to a single stage technique include avoidings need to re-elevate the
               flap for tendon graft and the ability to start earlier active ROM rehabilitation. With potential expedition
               however comes more risk. Considering the significantly higher rate of complications mostly relating to
               donor site graft loss and delayed healing of foot wounds, the radial forearm flap lends to less donor site
               morbidity for immediate composite reconstruction.

               Multiple staged reconstruction is commonly utilized for large composite defects . The procedure allows
                                                                                    [28]
               for wound closure and fracture union while tendon reconstruction is commonly delayed to subsequent
               procedures. The staged approach resulted in acceptable functional outcomes with no significant difference
               in total active motion or grip strength and no significant complications. Good to excellent total active
                                                                                                       [29]
               motion has previously been reported in two stage technique with rod placement for extensor zone six .
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