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Page 2 of 10                                         Crystal et al. Plast Aesthet Res 2019;6:1  I  http://dx.doi.org/10.20517/2347-9264.2018.69

               INTRODUCTION
               Initiated intentionally or as a result of natural disaster, mass casualty incidents (MCIs) continue to pose
               a significant challenge for emergency medical resources and multidisciplinary trauma teams. From
               earthquakes to landslides, geographical disasters frequently highlight multi-national relief efforts in resource
               constrained environments. In an era of domestic and international terrorism, deliberate episodes of mass
               violence utilizing explosives and firearms have disturbed the core of social intimacy and tested the resilience
               of regional care centers. Of particular concern in MCIs are crush and blast injuries to the upper and lower
               extremities, etiologies of which are rooted in the diversity of disaster types.

               Specifically, the polytrauma associated with explosions results from a primary high-pressure blast wave and
               secondary discharge of fragmented projectiles causing injuries ranging from soft tissue loss to complete
                                  [1,2]
                                                                                                        [2]
               traumatic amputation . In a clinical review of conflict and terrorist related trauma, Dussault et al.
                                                                                                        [3]
               found that on average, 54% of blast injuries affect the extremities. Similarly, a review by Clover et al.
               concluded that 60% of earthquake injuries are thought to localize to extremities, with 8%-13% associated
               with significant open fractures. The broad mechanisms of injury and bodily involvement seen within MCIs
               suggests an indispensable role for plastic surgeons in multidisciplinary teams comprised of colleagues from
                                                                    [4]
               various specialties including orthopedic and trauma surgery . As disasters become unfortunately more
               unexceptional, plastic surgeons need to prepare for and respond to civilian MCIs.

               With the evolution of extremity reconstruction from skin grafts to local tissue rearrangements and
               microvascular free flap transfer, painstaking decisions regarding limb salvage efforts in MCIs must be
               determined by plastic surgeons. This concept is further influenced by resource constrains particular to the
               region where a disaster occurs. The purpose of this study is to highlight the various means of upper and
               lower limb reconstruction following MCIs.


               METHODS
               A review of the literature was performed using the following MEDLINE search terms: (“Limb
               Salvage”[Mesh] OR Extremity Reconstruct*[tiab] OR “Surgery, Plastic”[MeSH] OR “Trauma Surgery”[Tiab]
               OR “Orthoplastic”[tiab]) AND (Mass Casualty[tiab] OR Terrorism[tiab] OR Earthquake[tiab] OR Blast
               Injur*[tiab] OR Explosion[tiab] OR Triage[tiab]). Titles and abstracts were screened for relevance. The
               initial search was limited to English-only articles and constrained to the past 30 years. Citations of assessed
               manuscripts were screened for applicable articles.


               RESULTS
               Three events including our institution’s experience with the 2013 Boston Marathon Bombing, the 2015-2016
               Ankara Terrorist Attacks, and the 2010 Earthquake in Haiti were specifically chosen to highlight extremity
               wounds associated with MCIs and the subsequent reconstructive role of plastic surgeons.


               Boston bombing
               On 15 Apr 2013, two pressure cooker bombs exploded along the route of the 117th Boston Marathon. The
                                                                                                        [5]
               ground-level positioning and shrapnel components of the explosives lead to significant extremity trauma .
                                                                                      [6]
               In total, 66% of admitted patients had lower extremity soft tissue and/or bony injuries .
               Our institution received 24 patients, 11 of whom were cared for by the plastic surgery service. All 11 patients
                                                                                     [7]
               had lower extremity injuries, while 4 had concomitant upper extremity injuries . Wounds were grossly
               contaminated by foreign bodies, foreign tissue, and weaponized debris deliberately intended to inflict
               secondary damage on patients. Three patients required lower extremity flap reconstruction in the acute to
               subacute setting.
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