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Author Instructions

            Letter to   A Letter to Editor is usually an open   /  Unstructured abstract   3-8   /
            Editor     post-publication review of a paper from   (optional). No more than keywords
                       its readers, often critical of some aspect   250 words.    (optional)
                       of a published paper. Controversial
                       papers often attract numerous Letters to
                       Editor
            Opinion    An Opinion usually presents personal   no more   None required.  3-8   /
                       thoughts, beliefs, or feelings on a topic. than two        keywords
                                                      pages
            Perspective  A Perspective provides personal   2000 max  None required.  3-8   /
                       points of view on the state-of-the-art                     keywords
                       of a specific area of knowledge and
                       its future prospects. Links to areas
                       of intense current research focus can
                       also be made. The emphasis should
                       be on a personal assessment rather
                       than a comprehensive, critical review.
                       However, comments should be put
                       into the context of existing literature.
                       Perspectives are usually invited by the
                       Editors.
            Research   Research Highlights discuss the main   1,200   None required.  3-6   /
            Highlight  advances made by the paper as well as  words max           Keywords
                       putting the findings of the study into the excluding
                       proper context of the field.   references,
                                                      figures,
                                                      and tables.
                                                      Table/
                                                      Figure: Max
                                                      of 1
           2.3 Manuscript Structure
           Trials, observational studies, systematic reviews, meta-analyses and qualitative research should be described and reported
           according  to  standard  guidelines,  as  presented  by  the  Equator  Initiative,  such  as  CONSORT,  STROBE  or  PRISMA
           guidelines.

           2.3.1 Front Matter
           2.3.1.1 Title
           The title of the manuscript should be concise, specific and relevant, with no more than 16 words if possible. When gene or
           protein names are included, the abbreviated name rather than full name should be used.

           2.3.1.2 Authors and Affiliations
           Authors’ full names should be listed. The initials of middle names can be provided. Institutional addresses and email
           addresses for all authors should be listed. At least one author should be designated as corresponding author. In addition,
           corresponding authors are suggested to provide their Open Researcher and Contributor ID upon submission. Please note
           that any change to authorship is not allowed after manuscript acceptance.
           2.3.1.3 Abstract
           Original research, systematic reviews, and meta-analyses require structured abstracts. The abstract should provide the
           context or background for the study and should state the study’s purpose, basic procedures (selection of study participants,
           settings, measurements, analytical methods), main findings (giving specific effect sizes and their statistical and clinical
           significance,  if  possible),  and  principal  conclusions.  It  should  emphasize  new  and  important  aspects  of  the  study  or
           observations, note important limitations, and not overinterpret findings. Clinical trial abstracts should include items that the
           CONSORT group has identified as essential. It is not allowed to contain results which are not presented and substantiated in
           the manuscript, or exaggerate the main conclusions. Citations should not be included in the abstract.

           2.3.1.4 Keywords
           Three to eight MeSH keywords should be provided, which are specific to the article, yet reasonably common within the
           subject discipline.
           2.3.2 Main Text
           Manuscripts of different types are structured with different sections of content. Please refer to Types of Manuscripts to
           make sure which sections should be included in the manuscripts. Please use correctly the terms “sex” (biological factors)
           and “gender” (identity and socio-cultural factors).

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