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Page 12 of 18 Chen et al. Microbiome Res Rep 2025;4:8 https://dx.doi.org/10.20517/mrr.2024.44
Figure 3. Graphical depiction of taxonomic differences at various PMA intervals. (A) subgroup A consists of studies in which infants
received 100% human milk (MOM/DHM). Arboleya et al. were excluded from this figure because they only reported differences within
[31]
the Bifidobacterium genus ; (B) subgroup B consists of studies in which infants received a combination of human milk (MOM/DHM)
and PF. Created with Biorender.com. This figure is a visual complement to Table 3, where taxonomic differences resulting from DHM
consumption in comparison to MOM at each time point are described. PMA: Postmenstrual age; MOM: mother’s own milk; DHM: donor
human milk; PF: preterm formula.
Other reported outcomes
Fecal metabolites
Arboleya et al. reported findings on fecal short-chain fatty acids (SCFA) content through gas
chromatography, identifying them as biomarkers of microbiota metabolism. The reported SCFAs were
acetate, propionate, and butyrate. At one month of life, concentrations of fecal propionate were higher in
the DHM group (P < 0.05). Concentrations of acetate were lower in the DHM group (P < 0.05).
[31]
Concentrations at the earlier time points showed no differences .

