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Figure 4. Infant microbiome composition in the SHIME gut model. (A) Family level taxonomic profile; (B) Genus level taxonomic profile;
(C) Relative abundance of all detected Bifidobacterium strains from samples after 48 h in the ex vivo fermentors for 8 different media
compositions for each infant fecal inoculum. Blank: No probiotics; iPF: intact protein formula; GOS: galactooligosaccharides; eHF:
extensively hydrolyzed formula; Bb: B. breve DSM 32583; Lf: L. fermentum CECT 5716; Lf + Bb: both probiotics added; VD: fecal inoculum
derived from vaginally delivered infant; CS: fecal inoculum derived from cesarean-delivered infant; SHIME: Simulator of the Human
Intestinal Microbial Ecosystem.
