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Special Issue Introduction:
Bacteriophages (or phages) are bacterial viruses that are ubiquitous in every environmental niche where
cognate host bacteria co-exist. Phage-host interactions are dependent on phage-encoded adhesion proteins
and host-encoded receptors, both of which dictate the ensuing infection process and evolutionary pathways
of both parties. Furthermore, in view of the current antibiotic crisis, phages are increasingly recognised as
alternative therapeutics both in human therapeutics as well as in animal husbandry and food production
systems. Therefore, phages are of biotechnological relevance in all facets of human life and wellbeing, and
in marine and terrestrial environmental niches. This Special Issue welcomes submissions of full research
articles, perspectives, reviews, meta-analyses or systematic reviews on all facets of phage biology, ecology,
interactions with their hosts and applications in food safety, human health and environmental monitoring.
Phage evolution and adaptation to bacterial phage-resistance systems or environmental pressures are key
to understanding how phages may be applied in a variety of niches, including agri-food, biotechnology
and human and/or animal therapeutics. Therefore, we particularly welcome submissions on the following
topics:
1. Phage-host interactions
2. Phage adhesion, replication and infection processes
3. Phage ecology and virome studies in human, food and environmental niches
4. Structural analysis of phages, phage proteins or complexes
5. Phage evolutionary processes and responses to host or environmental pressures
6. Bacterial anti-phage systems and their characterisation
7. Phage applications in food safety, human/animal therapeutics or pathogen detection systems
8. Functional genomics or functional characterisation of phage-derived proteins
9. Comparative phage genomics and taxonomy
10. Prophages, their diversity and their associated impact on their host
etc.

