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Oo et al. Mini-invasive Surg 2019;3:13  I  http://dx.doi.org/10.20517/2574-1225.2019.02                                                Page 7 of 9


               reconstruction. Minimally invasive approach is promising especially in experienced hands however more
               data on long-term oncological results is needed.


               Multimodality treatment is superior to surgery alone in locally advanced resectable GEJ tumours. The
               advantages of neoadjuvant or perioperative treatment are downstaging of tumour, reducing the risk of
               recurrence, improving rates of R0 resection and improving outcomes after complete resection. At present,
               there is no global consensus on the optimal multimodality management of GEJ tumours. Further studies
               are needed to explore the optimal treatment strategy including surgical approach, sequence and regimen of
               multimodality management .


               DECLARATIONS
               Authors’ contributions
               Oo AM and Ahmed S contributed equally to literature search and writing of manuscript.

               Availability of data and materials
               Not applicable.

               Financial support and sponsorship
               None.

               Conflicts of interest
               The authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               Not applicable.

               Consent for publication
               Not applicable.

               Copyright
               © The Author(s) 2019.

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