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Page 4 of 19                                                                               Maqboul et al. Mini-invasive Surg 2021;5:44   https://dx.doi.org/10.20517/2574-1225.2021.54


                             Table 1. Robotic intracorporeal neobladder study series: the perioperative outcomes

                                                               Number of      Number of      Median OT  EBL        Patients had      Number of events of           Number of events of           Median length of
                                                 Technique
                              Study                            patients had   patients had  (min) in      (mL) in  transfusion in    complication Clavien-Dindo  complication Clavien-Dindo  hospital stay
                                                 of RIN
                                                               RARC           RIN            RIN          RIN      RIN               ≥ III at 30 days in RIN       ≥ III at 90 days in RIN       (days) in RIN
                                        [39]
                              Collins et al.   2014  Studer U  147            80             420          n/a      n/a               n/a                           n/a                           n/a
                                     [40]
                              Goh et al.   2012  Studer U      15             8              450          225      3                 2                             2                             8
                                         [5]
                              Hosseini et al.  2020 Studer U   158            158            363          300      n/a               35                            10                            8
                                         [20]
                              Obrecht et al.     Modified      12             12             575          600      n/a               n/a                           n/a                           n/a
                              2020               Studer
                                        [41]
                              Tyritzis et al.   2013  Studer U  70            70             420          500      3                 22                            13                            9
                                       [42]
                              Desai et al.   2014  Studer U    132            132            456          430      6                 20                            17                            10.6
                                        [13]
                              Tuderti et al.   2020 Padua      11             11             255          n/a      n/a               0                             n/a                           7
                                            [43]
                              Schwentner et al.     Studer U   62             62             476          385      n/a               16                            16                            17
                              2015
                                    [44]
                              Gu et al.   2020   Studer U      12             12             419          400      8                 1                             1                             14.5
                                         [23]
                              Jonsson et al.   2011 Modified   45             36             480          625      n/a               3                             5                             9
                                                 Studer

                             RIN: Robotic intracorporeal neobladder; RARC: robot-assisted radical cystectomy; OT: operating time; EBL: estimated blood loss.



                             to out either side of 6 o’clock, and the suturing is completed circumferentially over a 22 Fr catheter, out to in on the ileal side, and in to out on the urethral
                             side.



                             Isolation of neobladder bowel segment and re-anastomosis of the bowel [Figure 4]: once the UIA is complete, as described above, the bowel is divided with
                             Endo-GIA™ Laparoscopic staplers which are passed through the “fourth arm” 15 mm port, once the robotic instrument has been removed. It is done 10 cm

                             above the UIA for the right ileal neobladder limb and 40 cm above the UIA for the left ileal neobladder limb. The ileum is then re-anastomosed using both a
                             60 mm and a 45 mm cartridge, finally closing the upper aspect of the anastomosed bowel with another 60 mm cartridge.



                             Detubularization of the ileal neobladder limbs and formation of the posterior plate [Figures 5 and 6]: both limbs of the neobladder are opened over the suction
                             instrument, except for 10 cm of the proximal aspect of the left ileal limb, which forms the “chimney”. Once detubularized, stay sutures are placed to bring the

                             medial sides of the top of the right ileal neobladder limb to the medial aspect of the left ileal neobladder limb, just at the bottom of the chimney. Two more stay
                             sutures are placed. First, 10 cm below the chimney, the medial aspect of the left ileal neobladder limb is sutured to the upper aspect of the ileum just above the
                             UIA. It leaves an open U-shaped loop of 20 cm of the left ileal neobladder limb on the left side of the pelvis. The final stay suture is placed at its most lateral

                             aspect, bringing the inner aspect of the upper and lower parts of this loop together. With the stay sutures in place, the different parts of the posterior plate are
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