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Sebastián-Tomás et al. Mini-invasive Surg 2019;3:30            Mini-invasive Surgery
               DOI: 10.20517/2574-1225.2019.29




               Review                                                                        Open Access


               Robotic total mesorectal excision: state of the art


               Juan Carlos Sebastián-Tomás , Sandra Santarrufina-Martínez , Sergio Navarro-Martínez , Paula
                                         1
                                                                                           1
                                                                    1
               Gonzálvez-Guardiola , Elías Martínez-López , Carmen Payá-Llorente , Eduardo García-Granero , Aleix
                                                                          1
                                                                                                 2
                                                     1
                                 1
               Martínez-Pérez 1
               1 Department of General and Digestive Surgery, Hospital Universitario Doctor Peset, Valencia 46017, Spain.
               2 Department of General and Digestive Surgery, Hospital Universitario y Politécnico La Fe, Valencia 46026, Spain.
               Correspondence to: Dr. Aleix Martínez-Pérez, Department of General and Digestive Surgery, Hospital Universitario Doctor
               Peset, Avenida Gaspar Aguilar 90, Valencia 46017, Spain. E-mail: aleix.martinez.perez@gmail.com
               How to cite this article: Sebastián-Tomás JC, Santarrufina-Martínez S, Navarro-Martínez S, Gonzálvez-Guardiola P, Martínez-
               López E, Payá-Llorente C, García-Granero E, Martínez-Pérez A. Robotic total mesorectal excision: state of the art.
               Mini-invasive Surg 2019;3:30. http://dx.doi.org/10.20517/2574-1225.2019.29
               Received: 27 Aug 2019    First Decision: 23 Sep 2019    Revised: 3 Oct 2019    Accepted: 11 Oct 2019    Published: 15 Oct 2019

               Science Editor: Nicola de'Angelis    Copy Editor: Cai-Hong Wang    Production Editor: Jing Yu



               Abstract
               Minimally-invasive conventional up-to-down laparoscopic approach is a widespread alternative for rectal cancer
               resection. Its potential benefits towards open surgery have been shown to rely, however, at secondary clinical outcomes,
               and its oncological non-inferiority compared with the traditional open approach has not been demonstrated yet. In
               this scenario, robotic-assisted minimally-invasive rectal resection has gained increasing popularity and promising
               expectancies. This narrative review aims to assemble the most updated evidence available and to discuss the future
               perspectives and challenges for this emergent surgical tool. The main benefit over conventional laparoscopy appears
               to be a reduction of conversion rates to open surgery, whereas the oncologic and functional outcomes seem similar
               than the other alternatives. Increased costs are the main limitation of the widespread of robotic technology. Low
               quality of the current evidence is remarkable.

               Keywords: Rectal cancer, total mesorectal excision, robotic surgery, minimally-invasive surgery




               INTRODUCTION
               In 2018, colorectal cancer (CRC) was the third most commonly diagnosed cancer (10.2%), and the second
               leading cause of cancer death (9.2%). Nearby two million of new CRC cases and more than 800,000 deaths
                                                    [1]
               were estimated to occur worldwide in 2018 . Surgery remains as the mainstay treatment for rectal cancer,
               improvements on the outcomes have been observed since the introduction and widespread of the principles

                           © The Author(s) 2019. Open Access This article is licensed under a Creative Commons Attribution 4.0
                           International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use,
                sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long
                as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license,
                and indicate if changes were made.


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