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Page 4 of 8                                      Alexandre et al. Mini-invasive Surg 2020;4:35  I  http://dx.doi.org/10.20517/2574-1225.2020.07



                                                                                                  Ref.


                                                                                              Kwon et al. [11]
                                                           Handy et al. [10]
                                          Nomori et al. [7]
                                                                                  Nakata et al. [23]
                                                                         Nomori et al. [24]
                                                                 Nagahiro et al. [6]
                                                  Bendixen et al. [8]
                                  Andreetti et al. [9]
                                                                                      Van der Ploeg et al. [12]
                                                                                              74
                                                                                      22
                                                                                                 RATS
                                                                                      17
                                                                 13
                                  75
                                          33
                                                                                  10
                                                           49
                                                                         28
                                                  103
                                                                                              227
                                                                                                   n
                                                                                                 VATS
                                                                 9
                                                                                  11
                                                                                      18
                                  70
                                          33
                                                  103
                                                                                              201
                                                                         28 × 3
                                                                                                 Open
                                                          TH and
                                                           192 (64
                                                        128 MS)
                                                                                                 RATS
                                                                                      4 + 1 ports
                                                                                              4 + 1 ports
                                                               incision
                                                incision
                                                                               incision
                                                                                                 VATS
                                                                                     access incision
                                          3 trocars, 6 cm
                                                           3 ports, 5-6 cm
                                 incision of 4 cm
                                                                                 anterior access
                                         anterior incision
                                                                                  2 ports, 6-10 cm
                                                          anterior incision
                                                                         3 trocars, 5-6 cm
                                  3 trocars, anterior
                                                                                              3 or 4 ports, access
                                                                                      3 ports, 4 cm anterior
                                                                 2 ports, 7 cm anterior
                                                  3 ports, 4 cm anterior
                                                                       axillary access incision
                                                                                             incision less than 5 cm
                                                sparing
                                                                       divided
                                                               sparing
                                                                                             sixth rib
                                                                   ALT 12 cm
                        surgery; VC: vital capacity; MS: median sternotomy; TH: thoracotomy; QOL: quality of life
                                                                                                   Description
                                                                                     rib resection
                                                           TH with muscle sparing
                                                                                                 Open
                                         cartilage but muscle sparing
                                                                   AAT 20-25 cm
                                                           MS
                                                                                  PLT division of the muscles and two ribs
                                                                         Muscles and one or two costal cartilages
                                          ALT of 12 cm long with section of a costal
                                                  ALT of 16 cm incision with muscle and rib
                                                                                                      Table 2. Comparative technical details of publications related to pain and repiratory recovery after lobectomy
                                  ALT of 9-10 cm with muscle and rib sparing
                                                                 PLT, one or two ribs resection and no muscle
                                                                                              PLT generally muscle sparing, resection of the
                                                                                      ALT of 20 cm long with muscle sparing and no
                                                                   PLT 30-35 cm
                                         (P < 0.05)
                                                                                         (P = 0.1966)
                                                               14 (P < 0.05)
                                                                                             (P = 0.0004)
                                                                                                  Pain
                                     week (P = 0.09)
                                                                                     5 (P = 0.51; 0.07; 0.26)
                                                           VATS = open (P = 0.08)
                                       VATS = ALT the second
                                  VATS > ALT (P = 0.000)
                                          VATS > ALT the first week
                                                                 VATS > PLT at POD 0, 1, 7,
                                                                                              MIS > open for acute pain
                                                  VATS > open for moderate
                                                to severe pain (P < 0.0001)
                                                                                      MIS = open at POD 1, 3 and
                                                                                           MIS = open for chronic pain
                                                0.014)
                                             (P = 0.13)
                                                                                                  QOL
                                                        Post op open < VATS for
                                                                                 and 0.03 at POD 7 and 14)
                                              VATS = open for QLQ-C30
                                                                               VATS = open for PaO 2  (P =
                                                  VATS > open for EQ5D (P =
                                                    social functioning (P < 0.05)
                                                                             0.054), SatuO2 (P = 0.063),
                                                      physical functioning, role and
                                                           Post op VATS > open for pain
                                                          and general health (P < 0.05)
                                                                           FVC (P = 0.1), FEV1 (P = 0.08)
                                                                                  VATS > open for PFR (P = 0.008
                                                             0.019)
                                                                   < 0.05/P < 0.001)
                            PLT: postero-lateral thoracotomy; MIS: minimally invasive surgery; PPOD: post operative day; PFR: peak flow rate; ALT: anterior limited thoracotomy; AAT: anteroaxillary thoracotomy; 6MWT: 6 min
                          walking test; FEV1: forced expiratory volume in 1 second; EQ5D: euroQol 5 dimensions; QLQ-C30: 30 item quality of life questionnaire; VATS: video-assisted thoracoscopic surgery; RATS: robotic assisted
                                                          and 6MWT (P = 0.14)
                                 and 6MWT (P = 0.000)
                                                                                                  Respiratory function
                                          VATS > ALT at one week for
                                       0.07) and 6MWT (P = 0.06)
                                                                       < 0.05) and 6MWT (P < 0.01)
                                                                         PLT < ALT/AAT/VATS for VC (P
                                                                 VATS > PLT for FVC (P = 0.011),
                                                                     AAT < ALT/VATS for 6MWT (P
                                                           VATS = open for FEV1 (P = 0.17)
                                         respiratory muscle strength (P =
                                  VATS > ALT for FEV1 (P = 0.028)
                                                               for FEV1 (P = 0.039) and VC (P =
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