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Page 8 of 11 Pais-Costa et al. Mini-invasive Surg 2018;2:33 I http://dx.doi.org/10.20517/2574-1225.2018.33

Table 3. QoL variables
b
Dimension Time Mean (SD) Multivariate model a Within subjects Baseline contrast c Last period contrast c
Physical functionating Baseline 96.9 (2.5) < 0.001 < 0.001
1 mo 93.1 (5.5) 0.002 0.002
3 mo 94.7 (5.2) 0.22 0.001
6 mo 95.5 (4.9) 0.98 0.004
12 mo 96.4 (3.9) 1.00 0.39
Social functionating Baseline 99.4 (0.7) 0.48
1 mo 98.8 (2.9)
3 mo 99.3 (1.3)
6 mo 99.6 (0.7)
12 mo 99.7 (0.6)
Mental health Baseline 91.7 (5.1) < 0.001 < 0.001
1 mo 93.2 (8.1) 1.00 1.00
3 mo 95.8 (4.2) 0.002 0.29
6 mo 97.9 (2.5) < 0.001 0.023
12 mo 97.2 (3) < 0.001 1.00
Bodily pain Baseline 97.4 (2.2) < 0.001 0.032
1 mo 95.4 (6.2) 0.81 0.81
3 mo 96.5 (4.5) 1.00 0.40
6 mo 97.6 (2.8) 1.00 0.09
12 mo 97.6 (2.8) 1.00 1.00
Vitality Baseline 97.6 (4.5) 0.009 0.001
1 mo 96.4 (4.8) 0.29 0.29
3 mo 95.7 (5) 0.044 1.00
6 mo 97.2 (3.4) 1.00 0.007
12 mo 98.5 (2.1) 1.00 0.035
Role physical Baseline 93.1 (2.9) 0.008 < 0.001
1 mo 90.3 (5.6) 0.01 0.01
3 mo 92.4 (3.8) 1.00 0.003
6 mo 92.8 (3.4) 1.00 1.00
12 mo 93.8 (2.9) 1.00 0.13
Role emotional Baseline 89.5 (7.1) < 0.001 < 0.001
1 mo 93.2 (5.2) 0.45 0.45
3 mo 95.9 (3.6) 0.005 0.69
6 mo 96.4 (3.1) 0.001 0.99
12 mo 97.3 (2.7) < 0.001 0.08
General health Baseline 95.6 (7.6) < 0.001 0.037
1 mo 97.5 (1.2) 1.00 1.00
3 mo 98.7 (1.2) 0.26 < 0.001
6 mo 99.1 (0.8) 0.11 0.61
12 mo 99.4 (0.9) 0.24 0.83
a Wilks’ lambda; F-test with Greenhouse-Geisser correction for violation of sphericity; post hoc pairwise comparisons with Bonferroni
c
b
adjustment for multiple comparisons. SD: standard deviation
short hospital stay, low morbidity (6.4%) and no mortality are clearly in accordance with the many
advantages reported in previous studies. The surgical margin was adequate in all cases, despite the lack of
intraoperative palpation that is inherent to this method. Late recurrence in this series was a rare event (only
6%), and given that they occurred distant in liver parenchyma, they could perhaps be attributed to more
aggressive biological behavior in those two cases.

Benign lesions of the liver usually occur in young patients, who care not only to achieve an early return to
work and sports practice, but also to maintain a good QoL and a pleasing body image. Giuliani et al. have
[15]
demonstrated that the laparoscopic approach was superior regarding the QoL of patients who underwent
operations due to benign liver lesions. In the present study we observed that there was an excellent