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            Special Issue

            A bespoke approach to rectal cancer resec on and management


            Guest Editor(s):                  Special Issue Introduction
            Gordon N Buchanan, MBBS, MD,      The  platform  or  mode  of  resecting  colorectal  cancer,  particularly  in  the  rectum  can
            MSc, FRCS                         inuence outcome – it is not just the expertise of the primary surgeon, but also the mode of
                                              resection (open vs. laparoscopic / robotic) that will not only predict the length of stay due
            The Lister Hospital, London, UK.
                                              to recovery but also the pathological parameters; enhanced recovery programmes further
                                              accelerate  patient  discharge.  There  are  very  important  team  factors  too;  the  skill  of
                                              assistance  is  magnied  in  laparoscopic  colorectal  resection  where  not  only  does  the
                                              camera operator need to understand and predict steps to smooth the operation, but also a
                                              second  assistant  particularly  in  left  sided  resection  can  retract  during  the  case  thus
                                              facilitating easier dissection – however for rectal cancer resection recent trials using a non-
                                              inferiority  assessment  for  oncological  parameters  have  shown  that  patients  undergoing  a
                                              laparoscopic  resection  fared  worse  than  those  undergoing    open  surgery.  The  robotic
                                              platform for rectal cancer allows a very detailed evaluation of pelvic anatomy due to its 3D
                                              visualisation  –  in  addition  the  wrist  element  afforded  by  the  robot  enables  excellent
                                              dissection of the TME plane, akin to the early descriptions popularised by Heald et al. but
                                              with a more magnied view. It is within the connes of the pelvis that robotic resection is
                                              likely to be of greatest benet, particularly for dissection of the mid and low rectum – the
                                              extra  robotic  arm  can  be  continuously  placed  in  a  similar  fashion  to  a  St  Mark's  pelvic
                                              retractor  in  open  surgery  thus  enabling  accurate  retraction  without  assistance  fatigue  or
                                              movement as may occur in open or standard laparoscopic surgery. This should both reduce
                                              conversion to open resection for low rectal cancer and improve oncological parameters,
                                              either equivalent to, or superior to those of open resection. Lower conversion rates should
                                              enhance earlier discharge and hospital recovery and reduce costs in the longer term. Whilst
                                              some  parts  of  the  world  have  high  rates  of  uptake for  laparoscopic  colorectal  resection,
                                              others lag far behind – the use of robotic surgery currently represents a small minority of
                                              cases;  going  forward  a  tailored  approach  to  colorectal  cancer  resection  needs  to
                                              encompass and study these important factors to achieve the best clinical and oncological
                                              outcomes  for  patients.  In  addition  other  modalities  including  transanal  total  mesorectal
                                              excision  (TaTME)to  enable  the  inferior  aspect  of  TME  dissection  and  its  place  also  need
                                              detailed evaluation.
                                              The  evolution  of  therapies  in  rectal  cancer  continues  to  expand  allowing  a  unique
                                              approach  through  local  excision,  chemoradio  -  and  contact  therapy,  watch  and  wait
                                              along with endoscopic and extended resection. This special edition aims to focus on the
                                              breadth of options available to clinicians and patients working in this arena.




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