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Mari et al. Mini-invasive Surg 2024;8:7 Mini-invasive Surgery
DOI: 10.20517/2574-1225.2023.103

Original Article Open Access

Predicting positive surgical margins in patients

treated with robot-assisted partial nephrectomy:
results from a prospectively maintained dataset of a

single tertiary referral center

Andrea Mari, Antonio Andrea Grosso, Simone Coco, Anna Cadenar, Mara Bacchiani, Luca Lambertini,
Eleana Massaro, Vincenzo Cangemi, Gemma Cianchi, Alessandro Sandulli, Francesco Lupo Conte,
Vincenzo Salamone, Riccardo Mariottini, Sofia Giudici, Fabrizio Di Maida, Laura Olivera, Rino Oriti, Sabino
Scelzi, Gianni Vittori, Lorenzo Masieri, Andrea Minervini

Department of Experimental and Clinical Medicine, University of Florence, Italy - Unit of Oncologic, minimally-invasive robotic
Urology and Andrology, Careggi Hospital, Florence 50134, Italy.
Correspondence to: Dr. Andrea Mari, Department of Experimental and Clinical Medicine, University of Florence, Italy - Unit of
Oncologic, minimally-invasive robotic Urology and Andrology, Careggi Hospital, Largo Brambilla 3, Florence, 50134, Italy. E-mail:
andrea.mari@unifi.it

How to cite this article: Mari A, Grosso AA, Coco S, Cadenar A, Bacchiani M, Lambertini L, Massaro E, Cangemi V, Cianchi G,
Sandulli A, Conte FL, Salamone V, Mariottini R, Giudici S, Di Maida F, Olivera L, Oriti R, Scelzi S, Vittori G, Masieri L, Minervini A.
Predicting positive surgical margins in patients treated with robot-assisted partial nephrectomy: results from a prospectively
maintained dataset of a single tertiary referral center. Mini-invasive Surg 2024;8:7. https://dx.doi.org/10.20517/2574-1225.
2023.103
Received: 29 Aug 2023 First Decision: 19 Mar 2024 Revised: 23 Apr 2024 Accepted: 24 May 2024 Published: 30 May 2024

Academic Editor: Giulio Belli Copy Editor: Dong-Li Li Production Editor: Dong-Li Li

Abstract
Aim: To identify the incidence and evaluate predictors of positive surgical margins (PSMs) after robot-assisted
partial nephrectomy (RAPN) in patients with clinical T1 renal cell carcinoma (RCC).

Methods: After securing ethics committee approval, we analyzed our institution’s prospectively maintained RCC
database. Our cohort included 1611 patients who underwent RAPN between January 2017 and December 2022.
Surgical specimens were evaluated using standard practices, and the International Society of Urological Pathology
(ISUP) grading system was employed.

Results: The majority (69.5%) of the 1,611 patients were males. Median age and Body Mass Index were 62.6 years
2
and 26.9 kg/m , respectively. Overall, 18.6% and 21.1% of the patients had an Eastern Cooperative Oncology Group

© The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
indicate if changes were made.

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