Page 57 - Read Online
P. 57
Aydin et al. J Transl Genet Genom. 2025;9:406-26 https://dx.doi.org/10.20517/jtgg.2025.108 Page 424
development. Mol Cell Biol. 2005;25:685-98. DOI
54. Biswas R, Bagchi A. NFkB pathway and inhibition: an overview. Comput Mol Biol. 2016;6:1. Available from: https://bioscipublisher.
com/index.php/cmb/article/view/2268. [Last accessed on 25 Dex 2025]
55. Papachristodoulou A, Heidegger I, Virk RK, et al. Metformin overcomes the consequences of NKX3.1 loss to suppress prostate
cancer progression. Eur Urol. 2024;85:361-72. DOI PubMed PMC
56. Sinha S, Bheemsetty VA, Inamdar MS. A double helical motif in OCIAD2 is essential for its localization, interactions and STAT3
activation. Sci Rep. 2018;8:7362. DOI PubMed PMC
57. Xie T, Pan S, Zheng H, et al. PEG10 as an oncogene: expression regulatory mechanisms and role in tumor progression. Cancer Cell
Int. 2018;18:112. DOI PubMed PMC
58. Glass GE, Mohammedali S, Sivakumar B, et al. Poland-Möbius syndrome: a case report implicating a novel mutation of the
PLXND1 gene and literature review. BMC Pediatr. 2022;22:745. DOI PubMed PMC
59. Wang ZG, Delva L, Gaboli M, et al. Role of PML in cell growth and the retinoic acid pathway. Science. 1998;279:1547-51. DOI
60. Zhu Y, Loukola A, Monni O, et al. PPP2R1B gene in chronic lymphocytic leukemias and mantle cell lymphomas. Leuk Lymphoma.
2001;41:177-83. DOI
61. Zhang X, He Y, Lee KH, et al. Rap2b, a novel p53 target, regulates p53-mediated pro-survival function. Cell Cycle. 2013;12:1279-
91. DOI PubMed PMC
62. Jeremiah N, Ferran H, Antoniadou K, et al. RELA tunes innate-like interferon I/III responses in human T cells. J Exp Med.
2023;220:e20220666. DOI PubMed PMC
63. Moreno CS. SOX4: The unappreciated oncogene. Semin Cancer Biol. 2020;67:57-64. DOI PubMed PMC
64. Citron BA, Saykally JN, Cao C, Dennis JS, Runfeldt M, Arendash GW. Transcription factor Sp1 inhibition, memory, and cytokines
in a mouse model of Alzheimer’s disease. Am J Neurodegener Dis. 2015;4:40-8. PubMed
65. Beishline K, Azizkhan-Clifford J. Sp1 and the ‘hallmarks of cancer’. FEBS J. 2015;282:224-58. DOI PubMed
66. McKee MD, Cole WG. Chapter 2 - Bone Matrix and Mineralization. In: Glorieux FH, Pettifor JM, Jüppner HBT-PB, editors.
Pediatric bone. San Diego: Elsevier; 2012. pp. 9-37. DOI
67. Goodman SR, Johnson D, Youngentob SL, Kakhniashvili D. The spectrinome: the interactome of a scaffold protein creating nuclear
and cytoplasmic connectivity and function. Exp Biol Med. 2019;244:1273-302. DOI PubMed PMC
68. Tang W, Shao Q, He Z, Zhang X, Li X, Wu R. Clinical significance of nonerythrocytic spectrin Beta 1 (SPTBN1) in human kidney
renal clear cell carcinoma and uveal melanoma: a study based on pan-cancer analysis. BMC Cancer. 2023;23:303. DOI PubMed
PMC
69. Layfield R, Hocking LJ. SQSTM1 and Paget’s disease of bone. Calcif Tissue Int. 2004;75:347-57. DOI PubMed
70. Breslin A, Denniss FA, Guinn BA. SSX2IP: an emerging role in cancer. Biochem Biophys Res Commun. 2007;363:462-5. DOI
PubMed
71. Aubrey BJ, Strasser A, Kelly GL. Tumor-suppressor functions of the TP53 pathway. Cold Spring Harb Perspect Med.
2016;6:a026062. DOI PubMed PMC
72. Shelton EL, Yutzey KE. Twist1 function in endocardial cushion cell proliferation, migration, and differentiation during heart valve
development. Dev Biol. 2008;317:282-95. DOI PubMed PMC
73. Song X, Zhang Y, Dai E, Du H, Wang L. Mechanism of action of celastrol against rheumatoid arthritis: a network pharmacology
analysis. Int Immunopharmacol. 2019;74:105725. DOI
74. Hesterkamp T, Whittaker M. Fragment-based activity space: smaller is better. Curr Opin Chem Biol. 2008;12:260-8. DOI PubMed
75. Sano M. Radicicol and geldanamycin prevent neurotoxic effects of anti-cancer drugs on cultured embryonic sensory neurons.
Neuropharmacology. 2001;40:947-53. DOI PubMed
76. Jiménez A, Carrasco L, Vázquez D. Enzymic and nonenzymic translocation by yeast polysomes. Site of action of a number of
inhibitors. Biochemistry. 1977;16:4727-30. DOI PubMed
77. Matthews H, Usman-Idris M, Khan F, Read M, Nirmalan N. Drug repositioning as a route to anti-malarial drug discovery:
preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate. Malar J. 2013;12:359. DOI
PubMed PMC
78. Xing Z, Su A, Mi L, et al. Withaferin a: a dietary supplement with promising potential as an anti-tumor therapeutic for cancer
treatment - pharmacology and mechanisms. Drug Des Devel Ther. 2023;17:2909-29. DOI
79. Hahm ER, Kim SH, Singh SV. Withaferin A inhibits breast cancer-induced osteoclast differentiation. Mol Carcinog. 2023;62:1051-
61. DOI PubMed PMC
80. Patra JK, Das G, Lee S, Kang S, Shin H. Selected commercial plants: a review of extraction and isolation of bioactive compounds
and their pharmacological market value. Trends Food Sci Technol. 2018;82:89-109. DOI
81. Deshaies M, Lamari N, Ng CKY, Ward P, Doohan FM. The impact of chitosan on the early metabolomic response of wheat to
infection by Fusarium graminearum. BMC Plant Biol. 2022;22:73. DOI PubMed PMC
82. Broomfield J, Hill M, Guglieri M, Crowther M, Abrams K. Life expectancy in Duchenne muscular dystrophy: reproduced individual
patient data meta-analysis. Neurology. 2021;97:e2304-14. DOI PubMed PMC
83. Matsuo M. Antisense oligonucleotide-mediated exon-skipping therapies: precision medicine spreading from Duchenne muscular
dystrophy. JMA J. 2021;4:232-40. DOI PubMed PMC
84. Wasala NB, Hakim CH, Chen SJ, Yang NN, Duan D. Questions answered and unanswered by the first CRISPR editing study in a

