Page 7 - Read Online

Chu et al. J Transl Genet Genom 2024;8:49-54 https://dx.doi.org/10.20517/jtgg.2023.47 Page 1

Chu et al. J Transl Genet Genom 2024;8:49-54 Journal of Translational
DOI: 10.20517/jtgg.2023.47
Genetics and Genomics

Editorial Open Access

Personalised genomic medicine is shaping the
future of healthcare

1
Annie T. W. Chu , Brian H. Y. Chung 1,2
1
Hong Kong Genome Institute, Hong Kong, China.
2
Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong,
China.
Correspondence to: Dr. Brian H. Y. Chung, Hong Kong Genome Institute, 2/F, Building 20E, Hong Kong Science Park, Hong
Kong, China. E-mail: bhychung@genomics.org.hk

How to cite this article: Chu ATW, Chung BHY. Personalised genomic medicine is shaping the future of healthcare. J Transl Genet
Genom 2024;8:49-54. https://dx.doi.org/10.20517/jtgg.2023.47

Received: 13 Nov 2023 Accepted: 18 Jan 2024 Published: 30 Jan 2024
Academic Editor: Sheng-Ying Qin Copy Editor: Fangling Lan Production Editor: Fangling Lan

The Human Genome Project, a pivotal moment in genomics, reached a significant milestone in 2003 by
completing 92% of the sequencing map of the human genome. As genomic technologies advance, the
Telomere-to-Telomere Consortium took on the task of filling in the remaining gaps in the genomic regions
[1]
in 2022 . This endeavour has provided invaluable insights into the field of genomics and its implications for
precision health. Precision medicine is an emerging paradigm in precise diagnosis, treatment, and efficient
surveillance of diseases, taking into account individual variability in genetics, lifestyle, and environment of
each patient . The transformative potential of precision medicine lies in its ability to move away from a
[2]
one-size-fits-all approach and embrace a patient-centric model . Diverse precision medicine initiatives
[3]
involving the sequencing of thousands to millions of human genomes have been launched worldwide,
aiming to bring genomics into healthcare [2,4,5] . Notable examples include the 100,000 Genomes Project in the
United Kingdom, the All of Us Research Program in the United States, and the China Precision Medicine
Initiative in China. These collaborative efforts exemplify the global commitment to leveraging advanced
technology to generate large-scale genomic data to predict or stratify the health risks of patients. Targeted
treatment and personalised care could be provided, unlocking the potential of improving quality of life and
helping to bring down healthcare costs. This special issue “Genomics & Precision Health” includes a total of
nine publications, leading by showcasing the launch of a population-based genome project in Hong Kong,

© The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0
International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing,
adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as
long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and
indicate if changes were made.

www.oaepublish.com/jtgg