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Chu et al. J Transl Genet Genom 2022;6:290-303 https://dx.doi.org/10.20517/jtgg.2022.02 Page 19

vision “To avail genomic medicine to all for better health and well-being”.

DECLARATIONS
Acknowledgments
We would like to thank all members of the HKGI in preparing the launch of the HKGP. This work would
not have been possible without the instrumental leadership and guidance from Dr Su-vui Lo, Chief
Executive Officer. We extend our gratitude to the Board of Directors and Advisory Committees for their
continuous support and advice. We also wish to acknowledge the support of the HKGP stakeholders: the
Food and Health Bureau; Hospital Authority; Department of Health; and Partnering Centres at The
University of Hong Kong/Queen Mary Hospital, The Chinese University of Hong Kong/Prince of Wales
Hospital, and Hong Kong Children's Hospital.

Authors’ contributions
Contributed intellectually and practically to this piece: Chu ATW, Fung JLF, Tong AHY, Chow SM, Chan
KYK, Yeung KS, Lo HM, Hong Kong Genome Project, Chung BHY

Availability of data and materials
Not applicable.

Financial support and sponsorship
Not applicable.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2022.

REFERENCES
1. Chung BHY, Chau JFT, Wong GK. Rare versus common diseases: a false dichotomy in precision medicine. NPJ Genom Med
2021;6:19. DOI PubMed PMC
2. Smedley D, Smith KR, Martin A, et al; 100; 000 Genomes pilot on rare-disease diagnosis in health care - preliminary report.
N Engl J Med 2021;385:1868-80. DOI PubMed
3. Stark Z, Schofield D, Martyn M, et al. Does genomic sequencing early in the diagnostic trajectory make a difference? Genet Med
2019;21:173-80. DOI PubMed
4. Wise AL, Manolio TA, Mensah GA, et al. Genomic medicine for undiagnosed diseases. Lancet 2019;394:533-40. DOI PubMed
PMC
5. Turro E, Astle WJ, Megy K, et al; Whole-genome sequencing of patients with rare diseases in a national health system.
Nature 2020;583:96-102. DOI PubMed PMC
6. Wheway G, Mitchison HM, Ambrose JC, et al. Opportunities and challenges for molecular understanding of ciliopathies - the 100,000
genomes project. Front Genet 2019;10:127. DOI PubMed PMC
7. Swanson CL, Kumar A, Maharaj JM, et al. Increasing genetic counseling referral rates through bundled interventions after ovarian
cancer diagnosis. Gynecol Oncol 2018;149:121-6. DOI PubMed
8. Dragojlovic N, Borle K, Kopac N, et al. The composition and capacity of the clinical genetics workforce in high-income countries: a
scoping review. Gene Med 2020;22:1437-49. DOI