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Page 8 of 12                               Adler et al. J Cancer Metastasis Treat 2019;5:45  I  http://dx.doi.org/10.20517/2394-4722.2019.03




































































               Figure 3. Postoperative sagittal total spine radiograph: posterior instrumentation L1-L5 with a screw and rod system, decompression via
               laminectomy, anterior stabilization with an insitu distractable vertebral body replacement of L3


                                                                                               [4]
               comorbidities, previous lines of treatment and the biological age must influence the decision . In tumor
               conferences a (neo-)adjuvant systemic therapy (endocrine therapy, Anti-HER-2 therapy, chemotherapy,
               osteoprotective therapy) is determined according to tumor load (TNM system) and biology. An adjuvant
               loco regional radiation therapy is mandatory in case of short edges of the resected areas in preparation
                    [4]
               slides .
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