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Topic: Role of Immune Cells in
the Tumor Microenvironment
The understanding that immune cells in, or missing from,
the tumor microenvironment (TME) are a central part
of cancer progression is now well established.
However, in part because these immune cells vary
so much in types, numbers and function, there are
certainly large gaps in both general and detailed
understanding of their roles. Having both broader and
deeper understanding of the role of immune cells in
Prof. Steven N. Fiering the TME will generate better understanding of cancer
biology and importantly, will lead to new options
Department of Microbiology and for treating tumors with various therapy strategies,
Immunology, Geisel School of Medicine at including immunotherapy. Additionally, many studies
Dartmouth, Lebanon, NH, USA. have linked immune TME infiltrate data in specific
cancers to patient outcome and therapy responses,
which can guide treatment application. Overall, the
current phase of cancer research is heavily focused on
the TME and we are confident this Special Issue will
help expand the understanding of immune cells in the
TME. The topic is broad, and we anticipate
publishing papers on a wide range of subjects grouped
within the “Role of immune cells in the tumor
microenvironment”.