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Prof. William P. Schiemann


                                          Vice Dean for Research, School of Medicine.
                                          Goodman-Blum Professor in Cancer Research, School of Medicine
                                          Professor, Department of Biochemistry
                                          Special Advisor to the Director, Case Comprehensive Cancer Center
                                          Director, Pilot Funding & Scientific Investments, CaseComprehensive Cancer Center






               William P. Schiemann is the Goodman-Blum Professor in Cancer Research in the Case Comprehensive Cancer
               Center. Dr. Schiemann received his BS in Premedicine from the University of Nevada-Reno in 1990. After receiving
               his PhD in Pharmacology from the University of Washington in 1996, Dr. Schiemann joined the laboratory of Dr.
               Harvey F. Lodish at the Whitehead Institute for Biomedical Research and MIT, where he initiated studies of the
               “TGFß- Paradox” and its role in driving breast cancer metastasis and disease recurrence. In 2001, Dr. Schiemann
               expanded these analyses as an independent investigator, initially as an Assistant Professor at National Jewish
               Health (Denver, CO) and subsequently as an Associate Professor at the University of Colorado School of Medicine
               (Aurora, CO). In 2010, Dr. Schiemann moved his research program to Case Western Reserve University and its
               Comprehensive Cancer Center, wherein he continues to elucidate the molecular mechanisms that underlie breast
               cancer development, metastasis, and disease recurrence.



               Topic: Breast Cancer Metastasis


               Although metastasis is the most lethal characteristic of breast cancer, our understanding of the
               molecular mechanisms that govern this event remains incomplete. The metastatic cascade is a highly
               complex and inefficient process that is subject to regulation by a host of intrinsic and extrinsic cellular
               mechanisms. The rapid development of powerful new technologies and models to study the breast
               cancer metastasis has greatly expanded our appreciation of the complexities associated with this last
               frontier of cancer biology. The Journal of Cancer Metastasis and Treatment will produce a Special
               Issue focused on breast cancer metastasis and its treatment.
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