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Kamal et al. J Cancer Metastasis Treat 2019;5:11 I http://dx.doi.org/10.20517/2394-4722.2018.89 Page 11 of 14

DECLARATIONS
Authors’ contributions
Manuscript writing: Kamal NH, El-Amrawy F, Ali HA, Nounou MI
Manuscript proofing and revisions: Edafiogho I, Nounou MI
Design: Nounou MI

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2019.

REFERENCES
1. Lin NU. Breast cancer brain metastases: new directions in systemic therapy. ecancermedicalscience 2013;7:307.
2. Palmieri D, Smith QR, Lockman PR, Bronder J, Gril B, et al. Brain metastases of breast cancer. Breast Dis 2006;26:139-47.
3. Yeh RH, Yu JC, Chu CH, Ho CL, Kao HW, et al. Distinct MR imaging features of triple-negative breast cancer with brain metastasis. J
Neuroimaging 2015;25:474-81.
4. Steeg PS, Camphausen KA, Smith QR. Brain metastases as preventive and therapeutic targets. Nat Rev Cancer 2011;11:352-63.
5. Lin NU, Claus E, Sohl J, Razzak AR, Arnaout A, et al. Sites of distant recurrence and clinical outcomes in patients with metastatic triple-
negative breast cancer: high incidence of central nervous system metastases. Cancer 2008;113:2638-45.
6. Aversa C, Rossi V, Geuna E, Martinello R, Milani A, et al. Metastatic breast cancer subtypes and central nervous system metastases. Breast
2014;23:623-8.
7. Clayton AJ, Danson S, Jolly S, Ryder WDJ, Burt PA, et al. Incidence of cerebral metastases in patients treated with trastuzumab for
metastatic breast cancer. Br J Cancer 2004;91:639-43.
8. Witzel I, Oliveira-Ferrer L, Pantel K, Muller V, Wikman H. Breast cancer brain metastases: biology and new clinical perspectives. Breast
Cancer Res 2016;18:8.
9. Lin X, DeAngelis LM. Treatment of brain metastases. J Clin Oncol 2015;33:3475-84.
10. Kotecki N, Lefranc F, Devriendt D, Awada A. Therapy of breast cancer brain metastases: challenges, emerging treatments and perspectives.
Ther Adv Med Oncol 2018;10:1758835918780312.
11. Adkins CE, Mohammad AS, Terrell-Hall TB, Dolan EL, Shah N, et al. Characterization of passive permeability at the blood-tumor barrier
in five preclinical models of brain metastases of breast cancer. Clin Exp Metastasis 2016;33:373-83.
12. O'Sullivan CC, Davarpanah NN, Abraham J, Bates SE. Current challenges in the management of breast cancer brain metastases. Semin
Oncol 2017;44:85-100.
13. Ballabh P, Braun A, Nedergaard M. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol Dis
2004;16:1-13.
14. Cook LJ, Freedman J. Brain tumors. New York: The Rosen Publishing Group; 2011.
15. Dauchy S, Miller F, Couraud PO, Weaver RJ, Weksler B, et al. Expression and transcriptional regulation of ABC transporters and
cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells. Biochem Pharmacol 2009;77:897-909.
16. Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ. Structure and function of the blood-brain barrier. Neurobiol Dis
2010;37:13-25.
17. Van Tellingen O, Yetkin-Arik B, De Gooijer MC, Wesseling P, Wurdinger T, et al. Overcoming the blood-brain tumor barrier for effective
glioblastoma treatment. Drug Resist Updat 2015;19:1-12.
18. Dong X. Current strategies for brain drug delivery. Theranostics 2018;8:1481-93.