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Page 8 of 11                         Pergolini et al. J Cancer Metastasis Treat 2018;4:33  I  http://dx.doi.org/10.20517/2394-4722.2017.84


                    P value  -  -  -   -            P value  0.001  -  0.001  0.006  0.152  0.003  -  0.001  0.070  (one-side)


                    Nonresected   patients,   median OS   (months)  -  -  -  -  Nonresected   patients,   median OS   (months)  7  -  5  6  6  12  -  16  16






                    Median   survival  (months)  27  67  29  NR  Median   survival  (months)  12  12  8  13  11  24  NR  53  14




                    5-year   survival (%)  NR  58.40  28  NR  5-year   3-year   survival   survival   (%)  (%)  NR  NR  NR  NR  NR  NR  5  NR  NR  NR  NR  NR  6  20.8  NR  NR  NR   NR





                    3-year   survival (%)  30  NR  NR  100  1-year   survival   (%)  NR  NR  NR  NR  NR  NR  80.3  NR  NR




                    1-year   survival (%)  NR  NR  NR  100  Neo/adjuvant   therapy  NR/NR  0/120  NR  NR/12  NR/15  NR/107  NR/112  NR/218  0/89

                 Table 3. Demographics and survival data from the cited lung resection studies for metastatic gastric cancer

                    Neoadj/  adjuvant   therapy (n)  NR  0/10  NR/18  0/3  Gastrectomy   total/subtotal  21/116  63/115  63/93  4/10  11/12  39/68  NR  NR  57/32



                    M/F   (n)  10/0  10/2  40/11  9/1  M/F  (n)  76/61  122/56  NR  14/10  NR  NR  143/40  NR  61/28

                    Mean age   (years)  64  56  68  67  Mean   age  (years)  58  58  NR  57  61  NR  60  NR  NR



                    Sample   (n)  10  12  51  10 Table 4. Demographics and survival data of patients undergoing palliative gastrectomy, with a comparison with nonresected patients  Sample   (n)  137  178  156  24  23  107  183  218  89



                    Median   follow-up   (months)  27  23  18  27 None of the 4 papers reported a comparison with nonresected patients. M: male; F: female; NR: not reported; OS: overall survival  Median  follow-up  (months)  NR  NR  NR  NR  NR  NR  NR  NR  NR



                    Recruitment   period  1985-2012  1998-2012  1980-2011  2003-2012  Recruitment   period  1992-2002  1992-2007  1989-1993  1990-2000  2000-2009  1999-2003  1994-2001  1997-2007  2008-2013





                    Year of   publication  2016  2012  2013  2014  Year of   publication  2010  2012  2002  2006  2012  2006  2008  2011  2016  M: male; F: female; NR: not reported; OS: overall survival




                    Country  Japan  Japan  Japan  Japan  Country  China  South Korea  The   Netherlands  USA  Finland  India  China  Greece  Japan/  South Korea/  Singapore





                    Study  Iijima   et al. [46]  Kobayashi   et al. [47]  Shiono   et al. [44]  Yoshida   et al. [45]  Study  Li et al. [48]  Ko et al. [49]  Hartgrink   et al. [50]  Saidi   et al. [51]  Kokkola   et al. [52]  Samarasam   et al. [53]  Lin et al. [54]  Sougioultzis   et al. [55]  Fujitani   et al. [58]
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