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Carvalho et al. Hepatoma Res 2020;6:6 I http://dx.doi.org/10.20517/2394-5079.2019.027 Page 5 of 6

HCC. Some studies have also suggested an impact of coffee consumption on HCC mortality and recent
studies showed that coffee consumption is associated with a reduced risk of HCC recurrence and longer
survival following liver transplantation. These results are encouraging, mainly due to the increase in the
incidence of HCC and its prognosis. Randomized studies are expected to confirm the results of mostly
observational studies.

DECLARATIONS
Authors’ contributions
Concept and design: Cotrim HP
Data acquisition: Carvalho KSD
Data analysis: Carvalho KSD, Cotrim HP
Manuscript preparation: Carvalho KSD, Cotrim HP
Critical revision and finalizing of the manuscript: Cotrim HP

Availability of data and materials
Not applicable.

Financial support and sponsorship
None.

Conflicts of interest
All authors declared that there are no conflicts of interest.

Ethical approval and consent to participate
Not applicable.

Consent for publication
Not applicable.

Copyright
© The Author(s) 2020.

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