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Page 6 of 9                Sioutas et al. Hepatoma Res 2021;7:26  https://dx.doi.org/10.20517/2394-5079.2020.111

               Table 1. Studies about pure laparoscopic donor hepatectomy for recipients with hepatocellular carcinoma
                                                         Donors                        Recipients
                                            Lee et al. [45]  (2018)  Lee et al. [83]  (2019)  Lee et al. [45]  (2018)  Lee et al. [83]  (2019)
                Country                     Korea           Korea          Korea           Korea
                Cases, n                    115             33             115             33
                HCC, n (%)                  -               -              78 (67.8)       7 (21.2)
                Graft weight (g)            715.4 ± 153.3   750.0 ± 194.0  -               -
                Estimated blood loss (mL)   394.1 ± 197.6   572.2 ± 438.9  NA              1650.0 ± 6082.7
                Operation time (min)        321.5 ± 57.2    433.7 ± 142.9  NA              597.5 ± 96.8
                Open Conversion, n (%)      NA              2 (6.1)        -               -
                Complications, n (%)  Overall  10 (8.7)     6 (18.2)       26 (22.6)       13 (39.4)
                              Clavien-Dindo I-II  7 (6.1)   3 (9.1)        NA              NA
                              Clavien-Dindo III-IV 3 (2.6)  3 (9.1)        NA              NA
                              Mortality     NA              NA             2 (1.7)         3 (9.1)
                              Rejection     -               -              NA              0 (0)
                Hospital stay (Day)         7.8 ± 1.8       9.7 ± 4.4      17.8 ± 8.7      24.0 ± 3.9

               Values are presented as mean ± standard deviation or frequency (%). NA: Not available; HCC: hepatocellular carcinoma; LT: liver transplantation.


               Table 2. Studies on laparoscopic-assisted liver transplantation
                                  Surgery   Patients             Age    Females  Blood   Operation   Deaths
                Study      Country                 Conditions
                                  type     (n)                   (years)  (%)   loss (mL) duration (min) (n)
                       [84]
                Eguchi et al.  Japan  HA + midline  9  Cirrhosis, Caroli’s   60 (44-  55.6  3940   741 (599-839)  1
                                  incision         disease       69)            (1300-
                                                                                18400)
                Soyama et al. [85]  Japan  HA + midline  29  Cirrhosis  NA  NA  7300    761 (578-1057)  0
                                  incision                                      (1300-
                                                                                18400)
                        [86]
                Dokmak et al.  France  PLH +   1   Neuroendocrine liver  52  100  400   400        0
                                  midline          metastases
                                  incision
               Values are presented as median (range). HA: Hand-assisted mobilization of the liver; NA: not available; PLH: pure laparoscopic total
               hepatectomy.


               DECLARATIONS
               Authors’ contributions
               Study concept, data analysis and interpretation, critical revision of the manuscript, final approval of the
               manuscript: Sioutas GS, Tsoulfas G
               Data acquisition, drafting of the manuscript: Sioutas GS


               Availability of data and materials
               Not applicable.


               Financial support and sponsorship
               None.


               Conflicts of interest
               Both authors declared that there are no conflicts of interest.
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