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Topic: Advancement of

                                                          Imaging Diagnosis of Liver

                                                          Cancer






                                                          Hepatocellular carcinoma (HCC) is a world-wide health
                                                          care problem, being the 6th most common cancer and
                                                          the 4th leading cause of cancer death. It is estimated
                                                          that more than 1 million patients will die from liver
                                                          cancer in 2030. It is also the fastest growing cause of
                                                          cancer death in the United States.
                                                          A majority of HCCs are now diagnosed by imaging
                                                          without tissue confirmation, so imaging plays a critical
                                                          role in the diagnosis and the management of HCC.
                                                          Imaging, however, is complicated due to underlying
                                                          cirrhosis.
                   Yuko Kono, MD, PhD                     Liver imaging reporting and data system (LI-RADS)
                    Clinical Professor of Medicine        is a standardized system for technique, interpretation,
                       and Radiology, Division of         reporting and data collection for the diagnosis of
                   Gastroenterology & Hepatology,         HCC in high risk patients and it now includes US
                University of California, San Diego,      surveillance, CT/MR/CEUS diagnostic algorithm and
                                         USA.
                                                          CT/MRI treatment response.
                                                          This special issue of Hepatoma Research, “Advancement
                                                          of imaging diagnosis of HCC”, will cover from HCC
                                                          surveillance  with  US and  alternative  approach  with
                                                          MRI, diagnosis and treatment response assessment
                                                          with CT, MRI and CEUS.
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