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Carvalho et al. Hepatoma Res 2020;6:6  I  http://dx.doi.org/10.20517/2394-5079.2019.027                                         Page 5 of 6


               HCC. Some studies have also suggested an impact of coffee consumption on HCC mortality and recent
               studies showed that coffee consumption is associated with a reduced risk of HCC recurrence and longer
               survival following liver transplantation. These results are encouraging, mainly due to the increase in the
               incidence of HCC and its prognosis. Randomized studies are expected to confirm the results of mostly
               observational studies.


               DECLARATIONS
               Authors’ contributions
               Concept and design: Cotrim HP
               Data acquisition: Carvalho KSD
               Data analysis: Carvalho KSD, Cotrim HP
               Manuscript preparation: Carvalho KSD, Cotrim HP
               Critical revision and finalizing of the manuscript: Cotrim HP


               Availability of data and materials
               Not applicable.


               Financial support and sponsorship
               None.


               Conflicts of interest
               All authors declared that there are no conflicts of interest.


               Ethical approval and consent to participate
               Not applicable.

               Consent for publication
               Not applicable.

               Copyright
               © The Author(s) 2020.

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