Page 151 - Read Online

Spiliopoulou et al. Cancer Drug Resist 2024;7:2 https://dx.doi.org/10.20517/cdr.2023.46 Page 19

16. Nishizuka Y, Sakakura T. Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science
1969;166:753-5. DOI PubMed
17. Astarita JL, Dominguez CX, Tan C, et al. Treg specialization and functions beyond immune suppression. Clin Exp Immunol
2023;211:176-83. DOI PubMed PMC
18. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2
receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol
1995;155:1151-64. PubMed
19. O’Garra A, Murphy K. Role of cytokines in determining T-lymphocyte function. Curr Opin Immunol 1994;6:458-66. DOI PubMed
+
+
20. Peng G, Li S, Wu W, Sun Z, Chen Y, Chen Z. Circulating CD4 CD25 regulatory T cells correlate with chronic hepatitis B infection.
Immunology 2008;123:57-65. DOI PubMed PMC
21. Apostolou I, von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J Exp Med 2004;199:1401-8. DOI
PubMed PMC
22. Safinia N, Scotta C, Vaikunthanathan T, Lechler RI, Lombardi G. Regulatory T cells: serious contenders in the promise for
immunological tolerance in transplantation. Front Immunol 2015;6:438. DOI PubMed PMC
23. Jonuleit H, Schmitt E. The regulatory T cell family: distinct subsets and their interrelations. J Immunol 2003;171:6323-7. DOI
PubMed
24. Abbas AK, Benoist C, Bluestone JA, et al. Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol
2013;14:307-8. DOI
25. Hsieh CS, Lee HM, Lio CWJ. Selection of regulatory T cells in the thymus. Nat Rev Immunol 2012;12:157-67. DOI PubMed
26. Josefowicz SZ, Rudensky A. Control of regulatory T cell lineage commitment and maintenance. Immunity 2009;30:616-25. DOI
PubMed PMC
+ +
27. Bilate AM, Lafaille JJ. Induced CD4 Foxp3 regulatory T cells in immune tolerance. Annu Rev Immunol 2012;30:733-58. DOI
PubMed
28. Yano H, Andrews LP, Workman CJ, Vignali DAA. Intratumoral regulatory T cells: markers, subsets and their impact on anti-tumor
immunity. Immunology 2019;157:232-47. DOI PubMed PMC
29. Georgiev P, Charbonnier LM, Chatila TA. Regulatory T cells: the many faces of Foxp3. J Clin Immunol 2019;39:623-40. DOI
PubMed PMC
+
30. Weinberg SE, Singer BD. Toward a paradigm to distinguish distinct functions of FOXP3 regulatory T cells. Immunohorizons
2021;5:944-52. DOI PubMed PMC
31. Huang L, Guo Y, Liu S, et al. Targeting regulatory T cells for immunotherapy in melanoma. Mol Biomed 2021;2:11. DOI PubMed
PMC
+ + - +
32. Saison J, Demaret J, Venet F, et al. CD4 CD25 CD127 assessment as a surrogate phenotype for FOXP3 regulatory T cells in HIV-1
infected viremic and aviremic subjects. Cytometry B Clin Cytom 2013;84B:50-4. DOI
+
33. Klein S, Kretz CC, Krammer PH, Kuhn A. CD127 low/- and FoxP3 expression levels characterize different regulatory T-cell
populations in human peripheral blood. J Invest Dermatol 2010;130:492-9. DOI
34. Ohue Y, Nishikawa H. Regulatory T (Treg) cells in cancer: can Treg cells be a new therapeutic target? Cancer Sci 2019;110:2080-9.
DOI PubMed PMC
35. Togashi Y, Shitara K, Nishikawa H. Regulatory T cells in cancer immunosuppression - implications for anticancer therapy. Nat Rev
Clin Oncol 2019;16:356-71. DOI PubMed
36. Huppert LA, Green MD, Kim L, et al. Tissue-specific Tregs in cancer metastasis: opportunities for precision immunotherapy. Cell
Mol Immunol 2022;19:33-45. DOI PubMed PMC
37. Eyoh E, McCallum P, Killick J, Amanfo S, Mutapi F, Astier AL. The anthelmintic drug praziquantel promotes human Tr1
differentiation. Immunol Cell Biol 2019;97:512-8. DOI PubMed
38. Zhao H, Liao X, Kang Y. Tregs: where we are and what comes next? Front Immunol 2017;8:1578. DOI PubMed PMC
39. Akimova T, Beier UH, Wang L, Levine MH, Hancock WW. Helios expression is a marker of T cell activation and proliferation.
PLoS One 2011;6:e24226. DOI PubMed PMC
+
40. Aksoylar HI, Boussiotis VA. PD-1 T cells: a foe in cancer immunotherapy? Nat Immunol 2020;21:1311-2. DOI PubMed PMC
reg
41. Dykema AG, Zhang J, Cheung LS, et al. Lung tumor-infiltrating T have divergent transcriptional profiles and function linked to
reg
checkpoint blockade response. Sci Immunol 2023;8:eadg1487. DOI PubMed PMC
+
42. Di Giorgio E, Wang L, Xiong Y, et al. MEF2D sustains activation of effector Foxp3 Tregs during transplant survival and anticancer
immunity. J Clin Invest 2020;130:6242-60. DOI PubMed PMC
43. Dolsten GA, Pritykin Y. Genomic analysis of Foxp3 function in regulatory T cells. J Immunol 2023;210:880-7. DOI PubMed
44. Trujillo-Ochoa JL, Kazemian M, Afzali B. The role of transcription factors in shaping regulatory T cell identity. Nat Rev Immunol
2023;23:842-56. DOI PubMed
45. Obradovic A, Ager C, Turunen M, et al. Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell
master regulators. Cancer Cell 2023;41:933-49.e11. DOI PubMed
46. Rapp M, Wintergerst MWM, Kunz WG, et al. CCL22 controls immunity by promoting regulatory T cell communication with
dendritic cells in lymph nodes. J Exp Med 2019;216:1170-81. DOI PubMed PMC
47. Iellem A, Mariani M, Lang R, et al. Unique chemotactic response profile and specific expression of chemokine receptors Ccr4 and