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Page 367                                                      Ganesan et al. Art Int Surg 2024;4:364-75  https://dx.doi.org/10.20517/ais.2024.68

               Table 1. Summary of AI advancements in wound diagnosis
                Study          AI framework and/or computational system  Outcome
                Identification and classification
                       [11]
                Birkner et al.  Deep convolutional neural network trained with images   Differentiate pyoderma gangrenosum from conventional leg
                               of pyoderma gangrenosum and leg ulcers  ulcer
                       [12]
                Hüsers et al.  Image detection and classification algorithms of the   Identify and classify venous leg ulcers and diabetic foot
                               YOLOv5, trained with 885 images of either wound  ulcers
                         [13]
                Swerdlow et al.   and   Convolutional neural network  Segmentation and classification of pressure injury images
                      [14]
                Zahia et al.
                       [15]
                Chang et al.   Deep learning based on superpixel segmentation  Pressure ulcer diagnosis
                       [16]
                Eldem et al.   “Alexnet architecture”, a deep learning tool  Classify pressure and diabetic wound images
                Lau et al. [18]  Smartphone application using a deep learning-based   Detection and stage classification of printed images of
                               object detection system              pressure injury wounds
                Sizing
                          [17]
                Mohammed et al.  “Swift”, a noninvasive digital tool using AI  Capture color calibrated images to identify wound
                                                                    boundaries, surface area, and depth
                      [19]
                Chan et al.    Mobile device application using YOLOv4, validated with  Detect length, width, and area of diabetic foot ulcers
                               144 photos
                Tissue identification
                Aldoulah et al. [20]  SEEN-B4 deep learning framework  Assess erythematous regions compared to an eschar or dry
                                                                    crust
                Veredas et al. [21]  Neural networks and Bayesian classifiers  Identify tissue types in wound images
                     [22]
                Lien et al.    Neural network model trained with three rounds of active  Detect the growth of granulation tissue in diabetic foot
                               learning                             ulcers
                     [23]
                Liu et al.     EfficientNet deep learning model     Create color-coded regions to identify ischemia and
                Viswanathan et al. [24]  AI-enabled noninvasive device, Illuminate®, capable of   infection based on real patient images of diabetic foot ulcers
                               autofluorescence imaging
               AI: Artificial intelligence; SEEN-B4: Swish-ELU EfficientNet-B4.













                                        Figure 1. Schematic of the elements that comprise wound care.


               printed images of pressure injuries using a deep learning-based object detection system . It has an
                                                                                               [18]
               accuracy of 63%, specificity of above 85%, and sensitivity of 73% . The app itself claims to provide a
                                                                         [18]
               “reasonable pressure injury staging support tool for lay carers” . With a moderately high specificity and
                                                                     [18]
               moderate sensitivity, providers should rely on this tool as a way to confirm suspected diagnosis rather than
               as a diagnostic tool itself. The technology specifically aimed to assist nursing home carers in accurate wound
               assessment and care planning to avoid downstream infection and hospitalization if the wound was
               otherwise not detected . Another mobile device application, described by Chan et al., can detect the length,
                                  [18]
                                                                        [19]
               width, and area of diabetic foot ulcers all without touching the ulcer .
               Aldoulah et al. present a novel Swish-ELU EfficientNet-B4 (SEEN-B4) deep learning framework that
                                                                                                       [20]
               specializes in the accurate assessment of erythematous regions compared to an eschar or dry crust .
               Similarly, Veredas et al. used neural networks and Bayesian classifiers to design a computational system for
               automatic tissue identification in wound images . Lien et al. used AI to detect the growth of granulation
                                                        [21]
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